Results 91 to 100 of about 1,825,336 (309)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Privatization and regional distribution of manufacturing in Turkey [PDF]
The state owned enterprises were crucial in the early stage of industrial development in Turkey. They were producer of basic consumption goods and contributed the building the entrepreneurial understanding, and hence the development of the private sector.
Fatma Dogruel, Suut Dogruel
core
Building Stronger Nonprofits Through Better Financial Management [PDF]
, 2012 The Wallace Foundation's four-year Strengthening Financial Management in Out-of-School Time initiative(SFM) was designed to improve the financial management systems of 26 well-respected Chicago nonprofits that provide out-of-school-time (OST) services ...
Lauren J. Kotloff, Nancy Burd
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Электронное приложение к Российскому юридическому журналу, 2019 The article is based on unpublished archival materials of the Center for Documentation of Public Organizations of the Sverdlovsk Region. The author examines the internal state of the Soviet police in the post-war period.
Mamyachenkov Vladimir
doaj +1 more source
Studia Paedagogica Ignatiana, 2016 The development of the Polish national movement in West Prussia began with the Spring of Nations. In the face of the Germanization policy of the authorities, Prussian Poles began to create their own organizations designed to maintain Polish identity and ...
Paweł Śpica
doaj +1 more source
Philanthropy and Equity: The Case of South Africa [PDF]
, 2005 This paper explores the potential role for philanthropy to promote greater equity in South Africa. It also aims to stimulate further discussion and debate about how philanthropic resources can best contribute to a more just and equitable South Africa ...
Christa L. Kuljian
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Road to Gender Equality: Global Trends and the Way Forward [PDF]
International organizations have expressed widespread agreement that gender equality is an important social and economic goal. Well-being is a multidimensional measure of material status and encompasses income, health, education, empowerment, relative ...
Seguino, Stephanie
core +1 more source
Scalable Privacy-Compliant Virality Prediction on Twitter [PDF]
, 2019 The digital town hall of Twitter becomes a preferred medium of communication for individuals and organizations across the globe. Some of them reach audiences of millions, while others struggle to get noticed.
Kowalczyk, Damian Konrad, Larsen, Jan
core +1 more source