Results 71 to 80 of about 278,348 (261)

The Directions of Educational Activities of Polish Organizations in West Prussia in the Late Nineteenth and Early Twentieth Century

open access: yesStudia Paedagogica Ignatiana, 2016
The development of the Polish national movement in West Prussia began with the Spring of Nations. In the face of the Germanization policy of the authorities, Prussian Poles began to create their own organizations designed to maintain Polish identity and ...
Paweł Śpica
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The Pioneers of Biodynamics in USA: The Early Milestones of Organic Agriculture in the United States

open access: yes, 2019
{"references": ["Northbourne, Lord, Look to the Land. 1940, London: Dent.", "Paull, J., Lord Northbourne, the man who invented organic farming, a biography. Journal of Organic Systems, 2014. 9 (1): p. 31-53.", "Carson, R., Silent Spring. Readers Union 1964 members' ed. 1962, London: Hamish Hamilton", "Paull, J., The Rachel Carson letters and the making
openaire   +3 more sources

“Turcoman Gypsies:” The intersectional/multiple identities of a peripatetic group and its historical segmentation

open access: yesRomani Studies
The early eighteenth-century Ottoman state correspondences reference a peripatetic group in Rumelia identified as the “Turcoman Gypsies” (Türkmān Ḳibṭīleri).
EGEMEN YILGÜR
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

TAXONOMY OF EDUCATIONAL OBJECTIVES OF EDUCATORS AND PARENTS OF PRESCHOOL CHILDREN IN THE CONTEXT OF THE REQUIREMENTS OF THE FEDERAL STATE EDUCATIONAL STANDARD

open access: yesОбразование и наука, 2016
The purpose of the article is to describe the taxonomic model thatallows diagnosing the levels of formation of the basic competencies of educators and parents in the conditions of realization of the federal state educational standard in preschool ...
V. B. Veretennikova   +2 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Early Results of a Co-operative Organization of Poultry and Egg Producers in New York State

open access: yesJournal of the American Association of Instructors and Investigators of Poultry Husbandry, 1915
Abstract The Poultry Producers’ Association of Ithaca, N. Y., is an organization of the farmers for the purpose of increasing their profits from the production of their poultry products. The operations of this Association were started about March 15, 1913, although the plan has been under careful discussion for a considerable time.
openaire   +1 more source

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