Results 181 to 190 of about 22,736,691 (304)

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

New South Carolina state documents July-August-September 2023

open access: yes
The quarterly New South Carolina State Documents publication by the State Library provides a list of state documents published by state agencies that have been cataloged and added to the South Carolina State Documents Depository.
South Carolina State Library
core  

Learning Collaboratives as a Community-Organizing Strategy to Improve Heart Health. [PDF]

open access: yesPrev Chronic Dis
Bradley C   +6 more
europepmc   +1 more source

The Business Organization of the Boston Manufacturing Company : The Early Development of Modern Management in the United States

open access: yesThe Business Organization of the Boston Manufacturing Company : The Early Development of Modern Management in the United States
3 KJ00000005766 ...
openaire   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Oxidative Stress as a Trigger Factor of Target Organs Damage at an Early Stage Development of Critical States

open access: yesGalician Medical Journal, 2015
Critical states (CS) in surgery, despite the success of the contemporary medical technology and pharmaceutical base, are still topical due to high rate of mortality. The mortality rate of acute diffuse peritonitis (ADP) is 20-92.8% and directly correlates with the number of affected organs involved in the pathological process. Under conditions of acute
openaire   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

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