Results 201 to 210 of about 54,498 (352)

Standardised early warning scoring system [PDF]

Clinical Medicine, 2006
Gavin D Barlow, Dilip Nathwani, Peter G Davey, Derek Bell, Ruth Paterson, Donald Macleod   +5 more
openaire   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

Integrating Modified National Early Warning Score 2, computed tomography staging, and laboratory markers for enhanced prognostic stratification in emphysematous pyelonephritis. [PDF]

World J Nephrol
Sevik C, Erbin A, Canat HL.
europepmc   +1 more source

The comparison of modified early warning score and Glasgow coma scale-age-systolic blood pressure scores in the assessment of nontraumatic critical patients in Emergency Department

, 2016
Özlem Köksal, Gökhan Torun, Erhan Ahun, Deniz Sığırlı, S B Güney, Mevlüt Okan Aydin   +5 more
openalex   +1 more source

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source

Evaluating Sepsis Mortality Predictions from the Emergency Department: A Retrospective Cohort Study Comparing qSOFA, the National Early Warning Score, and the International Early Warning Score. [PDF]

J Clin Med
Devia-Jaramillo GA, Erazo-Guerrero L, Laguado-Castro V, Alfonso-Parada JM.   +3 more
europepmc   +1 more source

Modified early warning (MEW) score: a low cost tool in predicting in-hospital outcomes of acutely ill medical patients

, 2014
Bushra Jamil, Mehreen Anis, Annie Merchant, Najeeha Talat, Zunirah Ahmed, Ashique Ali   +5 more
openalex   +1 more source

Predictive Performance of Lactate-Integrated Early Warning Scores in Non-Traumatic Critically Ill Adults: A Prospective Study [PDF]

Ali Ünal, Nese Çolak, Esra Deniz Goktepe, Suleyman Gedik, Abdülaziz Doğan   +4 more
openalex   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Corrigendum: National Early Warning Score for Predicting Clinical Outcome of Acute Pulmonary Embolism in Intermediate-High Risk Patients. [PDF]

TH Open
Overgaauw AJC, Nossent EJ, Meijboom LJ, Serne EH, Smulders YM, Nanayakkara PWB, Bogaard HJ, Tuinman PR, Klok FA.   +8 more
europepmc   +1 more source