Results 261 to 270 of about 836,996 (354)

Stress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer

Advanced Science, EarlyView.
Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao, Xuliren Wang, Han Zhu, Ling Yao, Qi Zhang, Zihan Zhai, Xinyi Lv, Xinyuan Xia, Yi Zhang, Xinya Lu, Xinyi Quan, Jiawen Yang, Xinwei Li, Jieyi Dong, Zhi‐ming Shao, Ruoxi Wang, Bingqiu Xiu, Jiong Wu, Sheng Chen   +18 more
wiley   +1 more source

Real-world data-driven early warning system for risk-stratified liver injury in hospitalized COVID-19 patients-Machine learning models for clinical decision support. [PDF]

Front Public Health
Xiong Y, Cai X, Lai X, Wang Y, Xin H, Song W, Lv F, Guo X, Yang G, Wu Y.   +9 more
europepmc   +1 more source

Integration of Early Warning Systems and Customer Segmentation Methods in the Financial Industry - A Systematic Literature Review

Alessandro Amato, Joerg Osterrieder, Marcos Machado   +2 more
openalex   +1 more source

Evaluation of the early warning, alert and response system after Cyclone Winston, Fiji, 2016

, 2019
Meru Sheel, Julie Collins, Mike Kama, Devina Nand, Daniel Faktaufon, Josaia Samuela, Viema Biaukula, Christopher Haskew, James Flint, Katrina Roper, Angela Merianos, Martyn Kirk, Eric J. Nilles   +12 more
openalex   +1 more source

Comment on “De Novo Reconstruction of 3D Human Facial Images from DNA Sequence”

Advanced Science, EarlyView.
This comment examines AI‐driven DNA‐based facial reconstruction, focusing on the Difface model. While such technologies promise biomedical and forensic applications, they pose significant ethical, legal, and methodological challenges. We emphasize transparency, benchmarking, and rigorous validation to avoid misinterpretation and misuse.
Jennifer K. Wagner, Nina Claessens, Caitlin M. Maloney, Peter Claes   +3 more
wiley   +1 more source

Development and validation of a dynamic early warning system with time-varying machine learning models for predicting hemodynamic instability in critical care: a multicohort study. [PDF]

Crit Care
Chiang DH, Jiang Z, Tian C, Wang CY.
europepmc   +1 more source

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

Advanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du, Zetao Dang, Baofeng Xu, Jiajun Xu, Dan Wang, Yuewei Zhang, Shoujun Zhu   +6 more
wiley   +1 more source

Modified National Early Warning Score 2, a reliable early warning system for predicting treatment outcomes in patients with emphysematous pyelonephritis. [PDF]

World J Nephrol
Krishnamoorthy S, Thiruvengadam G, Sekar H, Palaniyandi V, Ramadurai S, Narayanasamy S.   +5 more
europepmc   +1 more source

<span>Traditional Ecological Knowledge based Early Warning Systems for Adaptation to Climate Change</span>

Bongurala Gangadhar
openalex   +1 more source

Spatio‐Temporal Proteomic Landscape Reveals Early Warning Signals of Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li, Jie Yuan, Min Gao, Jibin Liu, Qinqin Wang, Yaqi Zhang, Mingtao Cao, Xiaolin Hu, Hui Yang, Jun Li, Chen Li, Xiaoguang Li, Hui Wang   +12 more
wiley   +1 more source