Results 31 to 40 of about 467,415 (261)

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim   +8 more
wiley   +1 more source

Hakiki ve Mecazi Yorumlar Bağlamında Sema ve Arza Canlılık Atfeden Ayetler

open access: yesEskişehir Osmangazi Üniversitesi İlahiyat Fakültesi Dergisi, 2021
Kur’an’da kâinatı oluşturan varlıkların birer ayet olduğu beyan edilir. Bu ifade söz konusu varlıkların Allah’ın yaratıcılığına, vahdetine ve yüce kudretine işaret ettiklerini akla getirir.
Ayşe Betül Oruç
doaj   +1 more source

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason   +14 more
wiley   +1 more source

Oronce Fine and L’esphere du monde: proprement dite Cosmographie (1549 and 1551)

open access: yesJournal of Early Modern Studies, 2023
The article explores tensions between cosmography and topography in maps and writings of Oronce Fine (1492-1555). Editor and illustrator of two editions of De sphaera of Johannes Sacrobosco (1517 and 1527), author of De sphaera mundi (1542), Fine ...
Tom Conley
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Editorial: Evolving Cosmographies

open access: yesJournal of Early Modern Studies, 2023
This editorial is intended to frame the special issue of the Journal of Early Modern Studies devoted to The Circulation of Cosmographical Knowledge in Early Modern Europe.
Sophie Chiari
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Victorian and Edwardian Virtual Reality: from Stoker to Forster

open access: yesCahiers Victoriens et Edouardiens, 2018
Fantasies of global transmission haunted the Victorian era, as demonstrated by one of George Du Maurier’s cartoons. Dracula engages with transmission in a dual way, turning Mina’s mind into a radio-system which the Count may switch on and off, whereas ...
Catherine Lanone
doaj   +1 more source

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