Results 51 to 60 of about 467,415 (261)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Simulator Posisi Matahari dan Bulan Berbasis Web dengan WebGL
Jurnal Nasional Teknik Elektro, 2014 Moon as a satellite of the earth has an important role for the life of the earth. Apart from being a source of illumination, moon also has an effect on the earth both on land and at sea.
Kamshory, Syafii
doaj
Science, 2018 Our planet is in a perilous state. The combined effects of climate change, pollution, and loss of biodiversity are putting our health and well-being at risk. Given that human actions are largely responsible for these global problems, humanity must now nudge Earth onto a trajectory toward a more stable, harmonious state.
openaire +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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Apophis source population and Earth encounter frequency of Apophis-like bodies
Astronomy & AstrophysicsContext. Asteroid (99942) Apophis will safely pass by the Earth in April 2029. This extraordinary event will be observable by the naked eye from Africa and western Europe. Aims.
Brož M. +6 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Notas sobre luta, Encantados e o povo Pataxó Hãhãhãi
ArgumentosThis article presents situations and reports of the relationships between the Pataxó Hãhãhãi People in the Caramuru-Paraguassu Indigenous Land, located between the municipalities of Pau Brasil, Itaju do Colônia and Camacã, in southern
Jurema Machado de Andrade Souza
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FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
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