Results 71 to 80 of about 502,399 (219)
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Two-stage formation of the Moon from accreting fragmentation and resonance captures
Context. In the canonical Moon-forming model, a Mars-sized object collided with Earth to produce a disk of debris from which the Moon is believed to have accreted. Aims.
Couturier Jérémy +2 more
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Eski Türklerde Şamanizm ve Günümüze Yansımaları
Eski Türklerin manevi dünyası, günümüzde bile hala büyük bir merak ve ilgi konusudur. Bu ilginin odağında ise şamanizm yer alır. Şamanizm, sadece bir inanç sistemi olmanın ötesinde, eski Türk toplumlarının dünya görüşünü, yaşam biçimlerini ve evrenle ...
Melisa Çamurcuoğlu Tosun
doaj
Caring for soils in war and peace: status and challenges towards land degradation neutrality
Purpose. This study aims to determine and summarise the current state of research and its key directions regarding the impact of military actions on soil and land resources in the context of the Russian-Ukrainian war, as well as to identify the main ...
Anatolii Kucher +2 more
doaj +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
An Initial Validation of the NASA TROPICS Pathfinder Microwave Radiometer Observations
The NASA Time-Resolved Observations of Precipitation structure and storm Intensity with a Constellation of Smallsats (TROPICS) Pathfinder CubeSat was placed into a sun-synchronous orbit by a SpaceX Falcon 9 launch vehicle during the June 30, 2021 ...
Amelia Gagnon +6 more
doaj +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source

