Results 91 to 100 of about 1,446,705 (302)
Correction to the references Nurhasan OY et al (2006) and Tseng KH et al (2020)
Earth, Planets and Space
doaj +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
EARTH Integrated Archaeology Rapporten 169
In opdracht van Infram BV heeft EARTH Integrated Archaeology in Januari-Juni 2021 een archeologisch bureauonderzoek (BO) inclusief archiefonderzoek uitgevoerd binnen twee deelgebieden in de gemeenten Molenlanden en Hardinxveld-Giessendam.
Rumping, BSc S. (EARTH Integrated Archaeology) +4 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The Physical Constitution of the Earth By Jean Coulomb and Georges Jobert. Translated by A. E. M. Nairn. Pp. xi + 328. (Edinburgh and London: Oliver and Boyd, Ltd., 1963.) 50s.
openaire +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Two-stage formation of the Moon from accreting fragmentation and resonance captures
Context. In the canonical Moon-forming model, a Mars-sized object collided with Earth to produce a disk of debris from which the Moon is believed to have accreted. Aims.
Couturier Jérémy +2 more
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