Results 101 to 110 of about 1,446,705 (302)

Een inventariserend veldonderzoek door middel van boringen (IVO-O), verkennende en karterende fase

open access: yes, 2017
Een inventariserend veldonderzoek door middel van boringen (IVO-O), verkennende en karterende ...
EARTH Integrated Archaeology B.V.
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The six days and the deluge: some ideas on earth history in the Royal Society of London 1660-1775 [PDF]

open access: yes, 1969
The influence of the biblical story of Creation and the Deluge on ideas of earth history during the period 1660-1775 is examined with particular reference to papers on the subject published in the Philosophical Transactions of the Royal Society of London.
Stokes, Evelyn
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Caring for soils in war and peace: status and challenges towards land degradation neutrality

open access: yesJournal of Innovations and Sustainability
Purpose. This study aims to determine and summarise the current state of research and its key directions regarding the impact of military actions on soil and land resources in the context of the Russian-Ukrainian war, as well as to identify the main ...
Anatolii Kucher   +2 more
doaj   +1 more source

Digital Earth: Big Earth Data

open access: yesInternational Journal of Digital Earth, 2014
Human beings have entered the age of ‘big data’. From 2005 to 2020, the digital universe is expected to grow by a factor of 300, from 130 exabytes to 40,000 exabytes, or 40 trillion gigabytes.
openaire   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

An Initial Validation of the NASA TROPICS Pathfinder Microwave Radiometer Observations

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
The NASA Time-Resolved Observations of Precipitation structure and storm Intensity with a Constellation of Smallsats (TROPICS) Pathfinder CubeSat was placed into a sun-synchronous orbit by a SpaceX Falcon 9 launch vehicle during the June 30, 2021 ...
Amelia Gagnon   +6 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

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