Results 61 to 70 of about 21,534 (252)

Mesenchymal Stromal Cell‐Mediated Intercellular Communication: Mapping the Interactome for Skeletal Muscle Homeostasis and Regeneration

open access: yesAdvanced Science, EarlyView.
Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu   +13 more
wiley   +1 more source

Tilted Circumbinary Planetary Systems as Efficient Progenitors of Free-floating Planets

open access: yesThe Astrophysical Journal Letters
The dominant mechanism for generating free-floating planets has so far remained elusive. One suggested mechanism is that planets are ejected from planetary systems due to planet–planet interactions.
Cheng Chen   +3 more
doaj   +1 more source

3D Chromatin Architecture Provides Insights Into Leaf Trait Variation Among Pear Species

open access: yesAdvanced Science, EarlyView.
ABSTRACT Three‐dimensional (3D) chromatin architecture plays a fundamental role in eukaryotic gene regulations, its functional significance in perennial fruit trees remains poorly characterized despite extensive applications in crop genomics. Here, we developed high‐resolution (∼5 kb) Hi‐C maps of Pyrus and compared 3D genomic architecture of three ...
Yueyuan Liu   +11 more
wiley   +1 more source

RedDots: Multiplanet system around M dwarf GJ 887 in the solar neighborhood

open access: yesAstronomy & Astrophysics
GJ 887 is a bright M dwarf in the solar neighborhood with two currently reported nontransiting exoplanets with periods of 9 d and 21 d, along with an additional unconfirmed signal at 50 d.
Hartogh C.   +9 more
doaj   +1 more source

Water, Conflict, and Peace

open access: yesOpen Rivers, 2018
We live on a water planet. As the writer Arthur C. Clark noted, if we didn’t happen to be land-dwelling creatures, we would call our planet Ocean, rather than Earth.
Peter Gleick
doaj   +1 more source

Mapping Agriculture on Mars

open access: yesCaliban: French Journal of English Studies, 2019
Le film de science-fiction de Ridley Scott, The Martian/Seul sur Mars (2015) joue sur plusieurs sources d'intérêt pour le spectateur. D'une part le film comporte de brillantes séquences consacrées à la technologie de la NASA telles que la récupération du
Raphaëlle Costa de Beauregard
doaj   +1 more source

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

open access: yesAdvanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen   +8 more
wiley   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

open access: yesAdvanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang   +12 more
wiley   +1 more source

Study of Free‐Space Optical Quantum Network: Review and Prospectives

open access: yesAdvanced Science, EarlyView.
Free from the constraints of fiber connections, free‐space quantum network enables longer and more flexible quantum network connections. This review summarizes and comparatively analyzes free‐space quantum network experiments based on ground stations, satellites, and mobile platforms.
Hua‐Ying Liu, Zhenda Xie, Shining Zhu
wiley   +1 more source

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun   +27 more
wiley   +1 more source

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