Results 31 to 40 of about 27,258 (263)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

3-D Low Earth Orbit Vector Estimation of Faraday Rotation and Path Delay

IEEE Access, 2015
An electromagnetic wave propagating through the ionosphere is subject to path delay and the depolarizing effect of Faraday rotation, both of which are dependent on global position and geometry.
Nicholas P. Lawrence, Hedley J. Hansen, Derek Abbott   +2 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Failure modes and inclined bearing capacity of a modified suction caisson in sand

Applied Ocean Research
Experiments and simulations are undertaken on the bearing behavior of a modified suction caisson (MSC) in sand under inclined load. Results show that the MSC movement modes include forward rotation, backward rotation, translations mainly along the ...
Yun Bai, Dayong Li
doaj   +1 more source

ON THE CONNECTION OF VARIATIONS OF THE VELOCITY OF THE EARTH ROTATION AND ITS SEISMIC ACTIVITY. THE EARTH‘S ENTRY INTO A NEW PHASE OF REDUCING OF THE ANGULAR VELOCITY ROTATION [PDF]

Vestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2017
Earth’s seismic activity demonstrates a distinct nonuniformity (heterogeneity) both in space and in time. The periods of intensification of seismic activity (SA) are followed by periods of its decline.
E.V. Sasorova, B.W. Levin
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Atmospheric dynamics of Earth-like tidally locked aquaplanets

Journal of Advances in Modeling Earth Systems, 2010
We present simulations of atmospheres of Earth-like aquaplanets that are tidally locked to their star, that is, planets whose orbital period is equal to the rotation period about their spin axis, so that one side always faces the star and the other side ...
Tapio Schneider, Timothy M Merlis
doaj   +1 more source

Calculation and analysis of earth pressure under limited displacement considering influences of internal friction angle

Yantu gongcheng xuebao, 2021
Taking the retaining wall in cohesive and cohesionless backfills as the research object, based on the existing results, a formula for calculating the earth pressure under the limited displacement considering the influences of internal friction angle is ...
ZHANG Le 1, DANG Fa-ning 1, WANG Xu 1, DING Jiu-long 1, GAO Jun 1
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source