Results 101 to 110 of about 6,682,022 (395)

Big data drives the development of Earth science

open access: yes, 2017
Big data is now a popular topic, becoming increasingly well known around the world, and yet the concept of big data and its implications are still novel. To discuss big data, it is appropriate to first talk about what is really meant by this term, and so
Huadong Guo
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Earth Science Education #7. GeoTrails: Accessible Online Tools for Outreach and Education

open access: diamond, 2023
Katie Maloney   +9 more
openalex   +2 more sources

The Algebra of Earth Science [PDF]

open access: yes
In this activity, students will graph carbon dioxide levels against temperature change over time and examine the data to look for trends. Another plotting exercise is provided in which they examine the relationship between the retreat of glaciers and sea

core  

Evolution of Earth-Lunar Transportation Systems [PDF]

open access: yes, 1962
Space science - earth-lunar missions - high-energy propellants and nuclear propulsion systems in manned space ...
Koelle, H. H.
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

The EPOS multi-disciplinary Data Portal for integrated access to solid Earth science datasets. [PDF]

open access: yesSci Data, 2023
Bailo D   +6 more
europepmc   +1 more source

NASA Earth and Space Science Explorers Poster [PDF]

open access: yes, 2007
This poster features several of the NASA Earth and Space Science Explorers, plus suggestions for using the series in the classroom. The series of online articles features NASA explorers, young and old, with many backgrounds and interests.
IGES
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

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