Results 51 to 60 of about 1,951,761 (334)

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

Fifteenth century earth science [PDF]

open access: yes, 1967
The earth science content of two late medieval encyclopedias, the Mirrour of the World and Higden's Polychronicon, both printed by William Caxton in the 1480's, is examined in relation to fifteenth century ideas about the physical nature of the earth and
Stokes, Evelyn
core   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Earth-Science Education: From all over the World to East-Timor [PDF]

open access: yes, 2012
Earth Science education (ESE) emerges as a relatively new research area and there is an unquestioned need for improving students´ abilities on that field (American Geological Institute, 2008), taking into account that it is important for students ...
Andrade, António   +3 more
core  

Latest Quaternary palaeoceanographic change in the eastern North Atlantic based upon a dinoflagellate cyst event ecostratigraphy

open access: yesHeliyon, 2016
The analyses of dinoflagellate cyst records, from the latest Quaternary sediments recovered from DSDP Core 610A taken on the Feni Ridge in the southern Rockall Trough, and part of core MD01-2461 on the continental margin of the Porcupine Seabight in the ...
Rex Harland   +5 more
doaj   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Implications of whole-disc DSCOVR EPIC spectral observations for estimating Earth's spectral reflectivity based on low-earth-orbiting and geostationary observations [PDF]

open access: yes, 2018
Earth’s reflectivity is among the key parameters of climate research. National Aeronautics and Space Administration (NASA)’s Earth Polychromatic Imaging Camera (EPIC) onboard National Oceanic and Atmospheric Administration (NOAA)’s Deep Space Climate ...
Chen, Chi   +13 more
core   +1 more source

Overcoming Data Scarcity in Earth Science

open access: yesData, 2020
The Data Scarcity problem is repeatedly encountered in environmental research. This may induce an inadequate representation of the response’s complexity in any environmental system to any input/change (natural and human-induced).
Angela Gorgoglione   +3 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

The Earth systems and Earth science informatics [PDF]

open access: yesEarth Science Informatics, 2008
Earth scientists collect, store, manage, process, and organize data about the different components of the Earth system, and about natural and simulated processes. The transition from data to information is achieved through computation, visualization, and other processes that make the data more meaningful to the scientists.
openaire   +2 more sources

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