Results 51 to 60 of about 262,952 (308)

Visualization analysis of ambient seismic noise research

Frontiers in Earth Science
In recent years, ambient seismic noise has gained considerable attention in seismology due to its potential to advance understanding of Earth’s subsurface dynamics and monitor anthropogenic activities.
Lihui Wu, Lihui Wu, Jinling Li, Sarina Bao, Qianbin Gong   +4 more
doaj   +1 more source

The Earth systems and Earth science informatics [PDF]

Earth Science Informatics, 2008
Earth scientists collect, store, manage, process, and organize data about the different components of the Earth system, and about natural and simulated processes. The transition from data to information is achieved through computation, visualization, and other processes that make the data more meaningful to the scientists.
openaire   +2 more sources

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

Reimagining Geoscience Education for Sustainability

Earth Science, Systems and Society
Geoscience is crucial for addressing sustainability challenges related to climate change, the energy transition, water resources management, and natural hazards.
Ellen P. Metzger
doaj   +1 more source

Mining sciences in the branch of Earth sciences

Izvestiya vysshikh uchebnykh zavedenii. Gornyi zhurnal, 2021
Problem statement. What is mining science? Is it craft, art of “treasure hunters”, or science? What underlies the theory of mineral extraction? What is its place within the system of knowledge of the environment? Discussion. Today there is no precise, clear, and conventional definition of mining science, its matter and object.
Galianov Aleksei, Iakovlev Viktor
openaire   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Geomorphology and Earth system science [PDF]

Progress in Physical Geography: Earth and Environment, 2010
Earth system science (ESS) is an approach to: ‘obtain a scientific understanding of the entire Earth system on a global scale by describing how its component parts and their interactions have evolved, how they function, and how they may be expected to continue to evolve on all timescales’ (Bretherton, 1998). The aim of this review is to introduce some
openaire   +4 more sources