Results 121 to 130 of about 1,438,141 (312)

Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism

FEBS Open Bio, EarlyView.
In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki, Hiroki Okanishi, Yoshikatsu Kanai, Ryoji Masui   +3 more
wiley   +1 more source

Inclusion of data uncertainty in machine learning and its application in geodetic data science, with case studies for the prediction of Earth orientation parameters and GNSS station coordinate time series

, 2022
Mostafa Kiani Shahvandi, Benedikt Soja
openalex   +1 more source

Applications of ISES for vegetation and land use [PDF]

Remote sensing relative to applications involving vegetation cover and land use is reviewed to consider the potential benefits to the Earth Observing System (Eos) of a proposed Information Sciences Experiment System (ISES).
Wilson, R. Gale
core   +1 more source

Relationship between science and technology in the New Zealand curriculum [PDF]

, 1997
New Zealand underwent major curriculum reforms in the early1990s. These reforms were determined by the New Zealand Curriculum Framework (Ministry of Education 1993), which provides an overarching framework for the development of curricula in New Zealand ...
Jones, Alister
core   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Earth observations from space: Outlook for the geological sciences [PDF]

Remote sensing from space platforms is discussed as another tool available to geologists. The results of Nimbus observations, the ERTS program, and Skylab EREP are reviewed, and a multidisciplinary approach is recommended for meeting the challenges of ...
Lowman, P. D., Jr., Short, N. M.
core   +1 more source

Time-variability in the Interstellar Boundary Conditions of the Heliosphere: Effect of the Solar Journey on the Galactic Cosmic Ray Flux at Earth

, 2011
During the solar journey through galactic space, variations in the physical properties of the surrounding interstellar medium (ISM) modify the heliosphere and modulate the flux of galactic cosmic rays (GCR) at the surface of the Earth, with consequences ...
A. Yeghikyan, B. Wolff, B.E. Wood, C. Heiles, C.P. Sonett, D.M. Meyer, E. Möbius, G. Hebrard, G.P. Zank, H. Müller, H. Müller, H.-R. Müller, Hans-Reinhard Mueller, I.G. Usoskin, J. Goldston Peek, J. Kirkby, J.D. Slavin, J.T. Gosling, K.G. McCracken, K.G. McCracken, L.A. Fisk, M. Salvati, M. Wolleben, M.A.C. Perryman, N.V. Pogorelov, P.C. Frisch, P.C. Frisch, P.C. Frisch, P.C. Frisch, P.C. Frisch, P.C. Frisch, P.C. Frisch, Priscilla C. Frisch, R. Lallement, R. Muscheler, R. Schönrich, R.A. Leske, R.A. Leske, R.A. Mewaldt, R.C. Bohlin, S. Redfield, S. Redfield, S. Redfield, S. Stanimirović, T.E. Holzer, U. Haud, V. Florinski, V. Florinski, W.R. Webber   +48 more
core   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Geochronology and Geochemistry of the Jiachadui Ganodiorite in Xizang and its Geological Implications

Kuangchan zonghe liyong
This is an article in the field of earth sciences. Magmatic rocks of the Gondwana Belt are one of the most popular problems in basic geological research on the Xizang-Qinghai Plateau.
YONGZHONGLADA, Junyong LU, SUOLANGDUNDAN, Xinghai LUO, Jianhua ZHU   +4 more
doaj   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source