Results 121 to 130 of about 1,474,341 (311)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Patterns in our planet: defining new concepts for the application of multi-scale non-equilibrium thermodynamics to Earth-system science

, 2009
Alison Ord, G. W. Hunt, B. E. Hobbs
openalex   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Monitoring flood risk evolution: A systematic review

iScience
Summary: Land-use change, climate change, human interventions, and socio-economic developments influence the evolution of the risk components hazard, exposure, and vulnerability, and consequently of flood risk.
Nele Rindsfüser, Andreas Paul Zischg, Margreth Keiler   +2 more
doaj   +1 more source

Earth Science Satellite Applications: Current and Future Prospects [PDF]

, 2015

openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

The association of climate-induced stressors on risk of negative sentiment: An analysis from 462 million geotagged tweets in Europe

iScience
Summary: This study examines how climate-induced health risks influence negative sentiments on European social tweets from 2015 to 2022. Analyzing over 400 million tweets using NLP tools (NLTK, LIWC22) and spatial-temporal aggregation at the NUTS2 weekly
Tareq Al-Ahdal, Sandra Barman, Barrak Alahmad, Stella Dafka, Elisa Gallo, Joan Ballester, Mikhail Sofiev, Marina Romanello, Till Bärnighausen, Michael Gertz, Joacim Rocklöv   +10 more
doaj   +1 more source

Representing earth science concepts using slowmation: influences on middle school students' conceptual change

, 2017
Reece Mills
openalex   +1 more source

Review of 'Developing the hertz art-science project to allow inaudible sounds of the Earth and Cosmos to be experienced'

, 2020

openalex   +1 more source

Optical Mineralogy in a Modern Earth Sciences Curriculum [PDF]

, 2007
Provides pedagogical insight concerning the skill of studying minerals The resource being annotated is: http://www.dlese.org/dds/catalog_SERC-NAGT-000-000-000-651 ...
Lamont-Doherty Earth Observatory, Columbia University
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