Results 151 to 160 of about 12,327,519 (291)
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Computer applications in the earth sciences : an international symposium
, 1969 "Proceedings of a conference on the state of the art held on campus at the University of Kansas, Lawrence on 16-18 June 1969. Sponsored by the Kansas Geological Survey, International Association for Mathematical Geology, and University of Kansas ...
Merriam, Daniel Francis
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Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
The History of Earth Sciences Society
, 2004 This site is the homepage for This History of Earth Science Society (HESS). The Society mission is to satisfy four basic needs of members, (1) to bridge the gap between humanities and the science, (2) to recognize that the history of earth science is a ...
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Geochemistry of alkaline-earth elements in the Amazon River
, 1979 Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Earth and Planetary Science, 1979.MICROFICHE COPY AVAILABLE IN ARCHIVES AND LINDGREN.Bibliography: leaves 47-52.by Wei Min Hao.M ...
Hao, Weimin
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Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Where on Earth Are the Earth Sciences? A Mixed-Methods Study of Environmental Justice Research Trends and Roadblocks to Engagement. [PDF]
GeohealthRosales Cortez O, Chen C.
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source