Results 171 to 180 of about 12,327,519 (291)

Magnetic resonance searches for Earth-sourced exotic nuclear spin-dependent interactions. [PDF]

Sci Adv
Wang Y, Huang X, Li J, Wang W, Kang X, Liu Y, Cong L, Budker D, Jiang M, Peng X.   +9 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Earth and Mineral Sciences Open Educational Resources

Pennsylvania State University's College of Earth and Mineral Sciences has made 79 full length courses and materials available to the public through their Open Educational Resources webpage. Courses are available for reuse by teachers, or by learners

core  

New ideas in Earth sciences

Известия высших учебных заведений: Геология и разведка, 2017
V. I. Lisov
doaj   +2 more sources

Immersive Virtual Reality for Earth Sciences [PDF]

Annals of computer science and information systems, 2018
Ilario Gabriele Gerloni, Vincenza Carchiolo, Fabio Roberto Vitello, Eva Sciacca, Ugo Becciani, Alessandro Costa, Simone Riggi, Fabio Luca Bonali, Elena Russo, Luca Fallati, Fabio Marchese, Alessandro Tibaldi   +11 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Space biology as a catalyst for the next biotech and longevity revolution. [PDF]

Exp Physiol
Kern C, Cook M, Reynolds E, Ashar A, Siew K, Johnson IRD, Grzesiak N, Jopling L, Christian M, Libera R, Gartner I, Ferreira MJS, Salem AK, Birch W, Dhanji N, Cullen DC, Sampaio JM, Oliveira D, Catchpole S, Richardson R, Milašius D, Bailey DM.   +21 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Author Correction: Coupled sulfur-silicon isotopes reveal supracrustal origin of Archean continents. [PDF]

Nat Commun
Shang K, Zhang J, Wang Z, Cawood I, Cui Y, Li M, Chang R, Shen Y, Zhao G.   +8 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source