Results 181 to 190 of about 253,500 (286)
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann+6 more
wiley +1 more source
Insects in bioregenerative life support systems: unlocking their role in space sustainability. [PDF]
Berggren Å+5 more
europepmc +1 more source
The Neglect of Earth Sciences in Elementary School
Louis A. Casciato, Seymour S. Greenberg
openalex +1 more source
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox+3 more
wiley +1 more source
Observation and simulation of chemically mediated searches in marine zooplankton. [PDF]
Franks SJ+3 more
europepmc +1 more source
Objective Gastrointestinal perforation (GIP) is a rare and life‐threatening safety concern associated with JAK inhibitors (JAKi). We aimed to review the evidence regarding the risk of GIP associated with the use of JAKi in patients with rheumatoid arthritis (RA) using a systematic review and network meta‐analysis approach.
Thipsukhon Sathapanasiri+7 more
wiley +1 more source
Objective We estimated the real‐world cost‐effectiveness of a standardized education and exercise therapy program (GLA:D) compared to usual care (UC) for people managing hip and/or knee osteoarthritis (HKOA). Methods We used a prospective matched cohort design to recruit people (aged >45 years) diagnosed with HKOA who used GLA:D or UC (not on a ...
Darren R. Mazzei+4 more
wiley +1 more source
Chiral Rare Earth Nanomaterials: Synthesis, Optical Properties, and Potential Applications. [PDF]
Zhao L+7 more
europepmc +1 more source