Results 131 to 140 of about 250,403 (271)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Graduate Catalog, 1969-1970 [PDF]
, 1969 https://scholar.valpo.edu/gradcatalogs/1005/thumbnail ...
Valparaiso University
core +2 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Post-glacial history of lake Näsijärvi, Finland, and the origin of the Tammerkoski Rapids
Fennia: International Journal of Geography, 2001 Lake Näsijärvi is a body of water of 265 km2 in the northern part of the Kokemäenjoki watercourse, central Finland. The lake was isolated from the Baltic Sea during the Ancylus Lake.
Matti Tikkanen, Heikki Seppä
doaj
Table-top earthquakes; a demonstration of seismology for teachers and students that can be used to augment lessons in earth science, physics, math, social studies, geography [PDF]
Open-File Report, 1998 openaire +1 more source
Future and present needs of remote sensing in geography [PDF]
Need for improved data analysis, information processing, research programs, and teaching methods in remote sensing in ...
Simonett, D. S.
core +1 more source
Kaupapa Māori and a new curriculum in Aotearoa/New Zealand [PDF]
, 2010 While geographical education is our focus in this paper, the broader colonial history of education is the backdrop against which we first view the principles of Māori geographies in education.
Chalmers, Lex +1 more
core
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source