Results 41 to 50 of about 1,185,812 (300)

Forced changes in El Niño–Southern Oscillation due to global warming and the associated uncertainties in ACCESS-ESM1.5 large ensembles

Frontiers in Climate, 2022
Understanding the forced response of El Niño–Southern Oscillation (ENSO) to future global warming (GW) is important for reliable climate projections; however, many important aspects of this response are yet to be fully understood.
Harun A. Rashid
doaj   +1 more source

Earth System Modelling with Galaxy

, 2020
EOSC-Nordic project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No ...
, Fouilloux, Iaquinta
openaire   +1 more source

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich, Manali Zope, Peter M. Fantozzi, Cassie N. Kline, Iris Paltin, Matthew C. Hocking   +5 more
wiley   +1 more source

Climate classification systems for validating Earth System Models

Environmental Research: Climate
Climate classification systems (CCSs) were developed in the 19th century to explain the global distribution of plants and animals, but were given a new life in the Earth physics community in the 21st century as a means to validate Earth System Models ...
Andrés Navarro, Francisco J Tapiador
doaj   +1 more source

Onset of giant planet migration before 4480 million years ago

, 2019
Immediately after their formation, the terrestrial planets experienced intense impact bombardment by comets, leftover planetesimals from primary accretion, and asteroids.
Abramov, Oleg, Brasser, Ramon, Kelly, Nigel M., Mojzsis, Stephen J., Werner, Stephanie C.   +4 more
core   +1 more source

Hierarchical Clustering of Seismic Activity Local Territories Globe [PDF]

, 2019
In article, the interrelation between energy parameters of Globe moving in a system Sun-Earth-Moon has been established. It includes features of a seasonal energy condition of an internal core of Earth and the key energy parameters of tectonic activity ...
Agazade, T. (Tural), Kalugin, V. (Vladimir), Pysklakova, O. (Olha), Tiutiunyk, V. (Vadym), Yaschenko, O. (Olexandr)   +4 more
core   +2 more sources

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Chemical Mechanisms and Their Applications in the Goddard Earth Observing System (GEOS) Earth System Model

Journal of Advances in Modeling Earth Systems, 2017
NASA's Goddard Earth Observing System (GEOS) Earth System Model (ESM) is a modular, general circulation model (GCM), and data assimilation system (DAS) that is used to simulate and study the coupled dynamics, physics, chemistry, and biology of our planet.
J. Eric Nielsen, Steven Pawson, Andrea Molod, Benjamin Auer, Arlindo M. da Silva, Anne R. Douglass, Bryan Duncan, Qing Liang, Michael Manyin, Luke D. Oman, William Putman, Susan E. Strahan, Krzysztof Wargan   +12 more
doaj   +1 more source