Results 41 to 50 of about 18,108,349 (299)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Influence of LV neutral grounding on global Earthing Systems [PDF]

, 2015
International Standards define a Global Earthing System as an earthing net created interconnecting local Earthing Systems (generally through the shield of MV cables and/or bare buried conductors). In Italy the Regulatory Authority for Electricity and Gas
Parise L., Torelli F., E. Morozova, Valtorta, G., PARISE, Giuseppe, Cafaro G., R. Tommasini, CAFARO, Giuseppe, Di Silvestre M. L., A. De Simone, Napoli, Roberto, Tummolillo F., G. Parise, MARTIRANO, Luigi, Riva Sanseverino, E., Valtorta G., Morozova E., Cafaro, G., DI SILVESTRE, Maria Luisa, M. L. Di Silvestre, Parise G., Di Silvestre, M.L., G. Valtorta, E. Pons, Pons, Enrico, Montegiglio P., Zizzo, G., P. Montegiglio, Colella, Pietro, G. Cafaro, MONTEGIGLIO, PASQUALE, Barresi, A., L. Martirano, Parise, L., L. Parise, De Simone, A., Martirano L., Sanseverino, E. Riva, P. Colella, Torelli, F., ZIZZO, Gaetano, Colella, P., Napoli, R., F. Torelli, Di Silvestre, M. L., F. Tummolillo, Zizzo G., Torelli, Francesco, Tommasini, R., RIVA SANSEVERINO, Eleonora, A. Barresi, R. Napoli, Parise, G., Martirano, L., Pons, E., De Simone A., PARISE, LUIGI, G. Zizzo, Barresi A., Tommasini, Riccardo, E. Riva Sanseverino, Riva Sanseverino E., Montegiglio, P., Tummolillo, F., Morozova, E.   +64 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Impact of First Tower Earthing Resistance on Fast Front Back-Flashover in a 66 kV Transmission System

Energies, 2020
Lightning stroke on a transmission tower structure is one of the major reasons that results in high voltages at the tower arms due to the excessive lightning current flowing through the transmission tower to earth.
Abdullah H. Moselhy, Abdelaziz M. Abdel-Aziz, Mahmoud Gilany, Ahmed Emam   +3 more
doaj   +1 more source

Effect of lightning mast placement on underground power cable jacket stress within high voltage substations

Journal of Mechatronics, Electrical Power, and Vehicular Technology, 2022
This study aims to investigate the impact of lightning masts placement on underground cables within high voltage substations. While the subject of lightning discharges near to underground cables has been covered with open cable runs and wind farms in ...
Mostafa Nazih
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Effect of high resistive barrier on earthing system

, 2003
Substation earthing provides a low impedance path and carries current into ground under normal and fault conditions without adversely affecting continuity of service.
Osman, M, Chen, G, Pilling, N
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Energy for Free in Spark-gap Earthing Circuits

Reports in Advances of Physical Sciences, 2023
In this paper, we study spark-gap earthing electrical circuits and show that such circuit’s power is greater than the power required to operate the circuit.
Ophir Flomenbom
doaj   +1 more source