Results 41 to 50 of about 574 (262)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Energy for Free in Spark-gap Earthing Circuits

open access: yesReports in Advances of Physical Sciences, 2023
In this paper, we study spark-gap earthing electrical circuits and show that such circuit’s power is greater than the power required to operate the circuit.
Ophir Flomenbom
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Study on Grounding System of the Metro Vehicles

open access: yes机车电传动, 2020
The function of the grounding system is related to the operation performance of the metro vehicles, so it has special significance to conduct a research.
Mingyuan HAO   +4 more
doaj  

A Novel Approach for Earthing System Design Using Finite Element Method [PDF]

open access: yesJournal of Intelligent Procedures in Electrical Technology, 2017
Protection of equipment, safety of persons and continuity of power supply are the main objectives of the grounding system. For its accurate design, it is essential to determine the potential distribution on the earth surface and the equivalent resistance
Sajad Samadinasab   +2 more
doaj  

Thin Conductor Modelling Combined with a Hybrid Numerical Method to Evaluate the Transferred Potential from Isolated Grounding System

open access: yesEnergies, 2019
Grounding systems are essential parts of substations and power generation stations. The evaluation of transferred potentials from an active grounding system to other passive ones or to any near conductors is an important aspect to be considered, because ...
Giovanni Aiello   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy