Results 71 to 80 of about 414 (226)

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A foundation model for the Earth system

Nature
Reliable forecasts of the Earth system are crucial for human progress and safety from natural disasters. Artificial intelligence offers substantial potential to improve prediction accuracy and computational efficiency in this field, however this remains underexplored in many domains.
Cristian Bodnar, Wessel P. Bruinsma, Ana Lucic, Megan Stanley, Anna Allen, Johannes Brandstetter, Patrick Garvan, Maik Riechert, Jonathan A. Weyn, Haiyu Dong, Jayesh K. Gupta, Kit Thambiratnam, Alexander T. Archibald, Chun-Chieh Wu, Elizabeth Heider, Max Welling, Richard E. Turner, Paris Perdikaris   +17 more
openaire   +5 more sources

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

An Investigation of Earth Grid Performance Using Graphene-Coated Copper

IEEE Access, 2015
Large power systems are normally operated with their neutral points directly earthed. At a major generating or switching station, this results in the provision of a large earth grid buried in the ground.
Amit Jyoti Datta, Richard Taylor, Geoffrey Will, Gerard Ledwich   +3 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Niveles de aterramiento y rayo: simulación de sus efectos sobre el consumidor; Earthing Levels and Lightning:Modeling and Simulation of Effects on Consumer

Revista Científica de Ingeniería Energética, 2011
El objetivo del trabajo es el análisis, a través de MatLab, de los efectos que tienen, sobre las tensionesy corrientes que circulan por la carga y el neutro de una instalación, la condición de considerar lossistemas de puesta ...
Miguel Castro Fernández, Sindhy Suárez Sotelo, Fernando de Armas García, Silvio Manuel Dorta Herrera   +3 more
doaj  

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Design and implementation of equipment for monitoring the salinity in the subsoil [PDF]

Ra Ximhai, 2012
Geochemical exploration equipments to explore the contaminants and structures geological in the subsoil come from abroad are expensive and sometimes parts for replacement are not available in the market.
Mariano Norzagaray Campos, Patricia Muñoz Sevilla, Cipriano García Gutiérrez   +2 more
doaj