Results 61 to 70 of about 10,476,796 (292)

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

ANALYSIS OF OVERVOLTAGES OCCURRING AT GROUNDING FAULTS IN A MEDIUM VOLTAGE NETWORK DEPENDING ON THE NEUTRAL TREATMENT [PDF]

open access: yesJournal of Sustainable Energy, 2017
The importance of the system earthing in electrical station 110kV/MV is much known, ways to treat the neutral directly affecting the behavior of the system regarding the maximum level of earth-fault currents and of the overvoltages that can occur.
MIRCEA. P. M.   +4 more
doaj  

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

A Single-Phase Ground Fault Line Selection Method in Active Distribution Networks Based on Transformer Grounding Mode Modification

open access: yesEnergies
Reliable fault line selection technology is crucial for preventing fault range expansion and ensuring the reliable operation of distribution networks.
Shi Su   +7 more
doaj   +1 more source

Electrolytic corrosion of water pipeline system in the remote distance from stray currents—Case study

open access: yesCase Studies in Construction Materials, 2016
Case study of corrosion failure of urban water supply system caused by the harmful effects of stray currents was presented. The failure occurred at a site distant from the sources of these currents namely the tramway and railway traction systems ...
Krzysztof Zakowski​   +6 more
doaj   +1 more source

Reimagining Earth in the Earth System

open access: yesJournal of Advances in Modeling Earth Systems
AbstractTerrestrial, aquatic, and marine ecosystems regulate climate at local to global scales through exchanges of energy and matter with the atmosphere and assist with climate change mitigation through nature‐based climate solutions. Climate science is no longer a study of the physics of the atmosphere and oceans, but also the ecology of the ...
Gordon B. Bonan   +11 more
openaire   +2 more sources

Addressing the Complexity of the Earth System [PDF]

open access: yesBulletin of the American Meteorological Society, 2010
This paper discusses the development of a prediction system that integrates physical, biogeochemical, and societal processes in a unified Earth system framework. Such development requires collaborations among physical and social scientists, and should include i) the development of global Earth system analysis and prediction models that account for ...
Nobre, C.   +9 more
openaire   +2 more sources

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

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