Results 31 to 40 of about 5,782,028 (302)

Increased GFAP immunoreactivity by astrocytes in response to contact with dorsal root ganglia cells in a 3D culture model [PDF]

open access: yes, 2007
Failure of repair mechanisms in the injured CNS is widely attributed to the inhibitory environment of the lesion site, most notably the formation of the glial scar which forms a physical and physiological barrier to axon regeneration.
East, Emma   +2 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Platon ve Aristo Mimesisinin Şekillendirdiği Sanat Anlayışları: Benim Adım Kırmızı Romanında İslam ve Batı Sanatları

open access: yesTurcology Research
Doğu ve Batı medeniyetleri arasında tarih boyunca çeşitli farklılıklar her zaman var olmuştur. Bu durum, birçok sosyal ve beşerî bilim dalının araştırma alanında önemli çalışmalara konu edilmiştir.
Esra Kürüm
doaj   +1 more source

European Studies

open access: yesVestnik MGIMO-Universiteta, 2014
The study of Western countries and teaching courses on the related subjects have longstanding and established tradition at MGIMO-University. The basis of this brilliant research and teaching tradition was laid down by such academicians as E.V.
V. O. Pechatnov, E. O. Obichkina
doaj   +1 more source

East is East, etc. [PDF]

open access: yesCancer Biology & Therapy, 2002
Menstrual cycle activity predisposes to ovarian epithelial tumors based on numerous epidemiological studies. We showed that the hormones involved in menstrual cycle regulation modulate cell cycle activity in these tumors in an accompanying paper. We investigated whether such hormones could also influence angiogenesis, an important determinant of tumor ...
openaire   +2 more sources

The East Midlands public procurement opportunities plan [PDF]

open access: yes, 2009
Public sector procurement activity accounts for a significant share of economic activity. This document sets out how the East Midlands can maximize the commercial benefits of these opportunities and contribute to the delivery of public policy in the ...
East Midlands Development Agency
core  

Mutually assured construction : resurrecting the West Texas missile silos [PDF]

open access: yes, 2016
A group of enthusiasts near Abilene, Texas are turning decommissioned, Cold War-era nuclear missile silos into homes, doomsday shelters, historical monuments and businesses, offering a unique glimpse into the blue-collar, do-it-yourself psyche of a ...
East, Andrew Joseph
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The importance of the 'Asian values' concept for modern political systems of East and Southeast Asia [PDF]

open access: yesMegatrend Revija, 2020
This paper analyzes the significance of the concept of "Asian values" for modern political systems of East and Southeast Asia. Taking the theoretical basis of one of the creators of the concept of "Asian values" - Lee Kuan Yew, as a starting point, the ...
Lončar Mirela
doaj  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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