Results 31 to 40 of about 5,833,618 (304)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

'When East Meets West': Perception of and Responses to Stigma Among Ethnic Minority Students from Eastern Indonesia in Java

Jurnal Psikologi
Ethnic minorities and indigenous people are two of the many groups at high risk of being stigmatized in society because of their identity. Such stigmatization might have diverse psychological and social impacts.
Syurawasti Muhiddin, Siti Nur Ainun Zakiyah, Mayrina Yanita Sitorus, Andrian Liem, Indra Yohanes Kiling, Elfydha Siti Safrina   +5 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Platon ve Aristo Mimesisinin Şekillendirdiği Sanat Anlayışları: Benim Adım Kırmızı Romanında İslam ve Batı Sanatları

Turcology Research
Doğu ve Batı medeniyetleri arasında tarih boyunca çeşitli farklılıklar her zaman var olmuştur. Bu durum, birçok sosyal ve beşerî bilim dalının araştırma alanında önemli çalışmalara konu edilmiştir.
Esra Kürüm
doaj   +1 more source

European Studies

Vestnik MGIMO-Universiteta, 2014
The study of Western countries and teaching courses on the related subjects have longstanding and established tradition at MGIMO-University. The basis of this brilliant research and teaching tradition was laid down by such academicians as E.V.
V. O. Pechatnov, E. O. Obichkina
doaj   +1 more source

East is East, etc. [PDF]

Cancer Biology & Therapy, 2002
Menstrual cycle activity predisposes to ovarian epithelial tumors based on numerous epidemiological studies. We showed that the hormones involved in menstrual cycle regulation modulate cell cycle activity in these tumors in an accompanying paper. We investigated whether such hormones could also influence angiogenesis, an important determinant of tumor ...
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The importance of the 'Asian values' concept for modern political systems of East and Southeast Asia [PDF]

Megatrend Revija, 2020
This paper analyzes the significance of the concept of "Asian values" for modern political systems of East and Southeast Asia. Taking the theoretical basis of one of the creators of the concept of "Asian values" - Lee Kuan Yew, as a starting point, the ...
Lončar Mirela
doaj  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Introduction

Études Britanniques Contemporaines
This issue of Études britanniques contemporaines stems from the annual SEAC conference organised by CECILLE and the University of Lille in the autumn of 2023.
Claire Hélie
doaj   +1 more source