Results 31 to 40 of about 1,078,746 (267)
ABSTRACT Background Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect in real‐life setting of these major changes is unknown, particularly in a Canadian environment. Procedure We aimed to assess
Maude Cigna +16 more
wiley +1 more source
Chinese theatre has gone through a drastic period of free development and exploration since 1980. Many new phenomena and tendencies have occurred during those years. The article is a panoramic summary of this productive and varied trajectory.
Lin Kehuan
doaj
The Artistic Role of Symbols in Ivan Gončarov's "Oblomov"
The article deals with the aesthetic characteristics of the symbols "home", "way", "light" and also examines the artistic role of these symbols in the structure of Oblomov's image.
Vladimir Brajuc
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
This study focuses on how Turkey is positioned between the East and the West through discourses and narratives on the imaginaries of its changing geopolitical trajectory. Specifically, it aims to investigate how the geopolitical and cultural mentality
Belçim Öztürk, Nurettin Özgen
doaj +1 more source
Comparison of national identities in Ukraine and Slovakia (in search of shared and conflict perceptions and stereotypes) [PDF]
The study compares identities of the Ukrainian and Slovak ethnicities; they both contribute with their respective uniqueness to Europe – in a certain sense – as a supranational community as well as to Europe consisting of differences and regional ...
Gita Geremešová
doaj
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The importance of the 'Asian values' concept for modern political systems of East and Southeast Asia [PDF]
This paper analyzes the significance of the concept of "Asian values" for modern political systems of East and Southeast Asia. Taking the theoretical basis of one of the creators of the concept of "Asian values" - Lee Kuan Yew, as a starting point, the ...
Lončar Mirela
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Menstrual cycle activity predisposes to ovarian epithelial tumors based on numerous epidemiological studies. We showed that the hormones involved in menstrual cycle regulation modulate cell cycle activity in these tumors in an accompanying paper. We investigated whether such hormones could also influence angiogenesis, an important determinant of tumor ...
openaire +2 more sources

