Results 31 to 40 of about 3,209,314 (313)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
This study focuses on how Turkey is positioned between the East and the West through discourses and narratives on the imaginaries of its changing geopolitical trajectory. Specifically, it aims to investigate how the geopolitical and cultural mentality
Belçim Öztürk, Nurettin Özgen
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Chinese theatre has gone through a drastic period of free development and exploration since 1980. Many new phenomena and tendencies have occurred during those years. The article is a panoramic summary of this productive and varied trajectory.
Lin Kehuan
doaj
Comparison of national identities in Ukraine and Slovakia (in search of shared and conflict perceptions and stereotypes) [PDF]
The study compares identities of the Ukrainian and Slovak ethnicities; they both contribute with their respective uniqueness to Europe – in a certain sense – as a supranational community as well as to Europe consisting of differences and regional ...
Gita Geremešová
doaj
The Artistic Role of Symbols in Ivan Gončarov's "Oblomov"
The article deals with the aesthetic characteristics of the symbols "home", "way", "light" and also examines the artistic role of these symbols in the structure of Oblomov's image.
Vladimir Brajuc
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
East-West Center review, Vol. 2 no. 3 (February 1966)
For more about the East-West Center, see http://www.eastwestcenter.org/East and West--a study in related cultural symbolism; Motivations of the student movement in Korea; Pearl Buck's problem with time in 'The Good Earth' trilogy--its effects on realism ...
East-West Center Grantees' Association
core +1 more source

