Results 211 to 220 of about 4,000,818 (351)

Evaluation of the Medicines and Healthcare products Regulatory Agency's introduction of a risk‐proportionate approach for clinical trials: An analysis of 4617 applications assessed between September 2023 and August 2024

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims The Medicines and Healthcare products Regulatory Agency (MHRA) introduced a risk‐proportionate approach to assess clinical trial applications for authorisation in August 2023. This study evaluates the impact of this approach on the timelines for reviewing proposals.
Andrea Manfrin   +6 more
wiley   +1 more source

The burden of malaria in East Africa: prevalence, risk factors, and control strategies. [PDF]

open access: yesMalar J
Bashir SG   +5 more
europepmc   +1 more source

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon   +12 more
wiley   +1 more source

Activism in the arts: Co‐researching cultural inequalities with young people during the COVID‐19 pandemic

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This paper explores the growing influence of young people's activism in UK museums and its educational implications. It draws on a five‐year collaborative programme (2019–2023) with young people of colour (16–28) in a university museum setting, focusing on a Young Collective established to address cultural inequalities.
Sadia Habib
wiley   +1 more source

Magnitude and predictors of gestational trophoblastic disease in East Africa: a systematic review and meta-analysis. [PDF]

open access: yesBMC Pregnancy Childbirth
Yilak G   +7 more
europepmc   +1 more source

A typology of schools across the four nations of the United Kingdom: Class, race and geography

open access: yesBritish Educational Research Journal, EarlyView.
Abstract In this paper we analyse the hierarchical field of schools across the United Kingdom during the transition to university and suggest that there are five socially distinct clusters of schools. Our five‐cluster typology of UK schools is composed of an established group of elite private and state schools, schools for the white rural and suburban ...
Sol Gamsu, Håkan Forsberg
wiley   +1 more source

Parental choice of private tuition: Valuing attention, judging quality and navigating access in England's underregulated supplementary education market

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Private supplementary education is burgeoning worldwide, and over 25% of English children have received private tutoring. The neoliberalisation of education and parents' responsibilisation for children's attainment have driven market growth, but not all can afford to participate.
Sarah L. Holloway   +2 more
wiley   +1 more source

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