Results 41 to 50 of about 202,381 (223)

Re-annotation of the Theileria parva genome refines 53% of the proteome and uncovers essential components of N-glycosylation, a conserved pathway in many organisms

BMC Genomics, 2020
Background The apicomplexan parasite Theileria parva causes a livestock disease called East coast fever (ECF), with millions of animals at risk in sub-Saharan East and Southern Africa, the geographic distribution of T. parva.
Kyle Tretina, Roger Pelle, Joshua Orvis, Hanzel T. Gotia, Olukemi O. Ifeonu, Priti Kumari, Nicholas C. Palmateer, Shaikh B. A. Iqbal, Lindsay M. Fry, Vishvanath M. Nene, Claudia A. Daubenberger, Richard P. Bishop, Joana C. Silva   +12 more
doaj   +1 more source

East Coast fever, a neglected tropical disease with an outdated vaccine approach?

Trends in Parasitology, 2022
Since its discovery, bovine theileriosis has caused major socioeconomic losses in sub-Saharan Africa. Acaricide resistance of the intermediate host, paucity of therapeutics, and lack of sufficiently cross-protective vaccines increase the risk of parasite
Jeannine Kolakowski, T. Connelley, P. Lukacik, M. Pfuhl, D. Werling   +4 more
semanticscholar   +1 more source

Estimating the societal disease burden of East Coast fever among rural cattle keeping households of Namwala District, Zambia

bioRxiv, 2021
The study aimed to estimate the disease burden of East Coast fever (ECF) among rural cattle keeping households of Namwala District of Zambia using Productivity Adjusted Life Years (PALYs).
N. Mwila, Chisoni Mumba, Omran Salih, Karen Sichibalo, Edgar Simulundu, Katendi Changula, S. Chitanga   +6 more
semanticscholar   +1 more source

Retrospective study on cattle and poultry diseases in Uganda

International Journal of Veterinary Science and Medicine, 2017
Cattle and poultry enterprises are among the major contributors to food security and socioeconomic empowerment of households in Uganda. However, various diseases constrain their productivity.
Joseph Byaruhanga, Dickson S. Tayebwa, Wilfred Eneku, Mathias Afayoa, Francis Mutebi, Susan Ndyanabo, Steven Kakooza, James Okwee-Acai, Robert Tweyongyere, Eddie M. Wampande, Patrick Vudriko   +10 more
doaj   +1 more source

Climate change influences on the geographic distributional potential of the spotted fever vectors Amblyomma maculatum and Dermacentor andersoni [PDF]

PeerJ, 2022
Amblyomma maculatum (Gulf Coast tick), and Dermacentor andersoni (Rocky Mountain wood tick) are two North American ticks that transmit spotted fevers associated Rickettsia.
Abdelghafar Alkishe, A. Townsend Peterson   +1 more
doaj   +2 more sources

Absolute quantification of the host-to-parasite DNA ratio in Theileria parva-infected lymphocyte cell lines [PDF]

, 2016
Theileria parva is a tick-transmitted intracellular apicomplexan pathogen of cattle in sub-Saharan Africa that causes East Coast fever (ECF). ECF is an acute fatal disease that kills over one million cattle annually, imposing a tremendous burden on ...
Bishop, Richard P., Daubenberger, Claudia A., Gotia, Hanzel T., Knowles, Donald P., Munro, James B., Silva, Joana C.   +5 more
core   +4 more sources

Proceedings: Onderstepoort Centenary Pan-African Veterinary Conference : foreword

Onderstepoort Journal of Veterinary Research, 2009
In 1908 a Pan-African Veterinary Conference formed part of the inauguration ceremony of the Onderstepoort Veterinary Laboratory. Attended by 18 delegates from 12 countries in southern Africa, including the four colonies and three protectorates forming
Editorial Office
doaj   +1 more source

Fusion to green fluorescent protein improves expression levels of Theileria parva sporozoite surface antigen p67 in insect cells [PDF]

, 2002
East Coast fever (ECF) is a fatal disease of cattle caused by the protozoan parasite Theileria parva. The development of a subunit vaccine, based on the sporozoite-specific surface antigen p67, has been hampered by difficulties in achieving high-level ...
Kaba, S.A., Musoke, A.J., Nene, V., Oers, M.M., van, Vlak, J.M.   +4 more
core   +2 more sources

Molecular epidemiology of Theileria parva in Eastern Democratic Republic of Congo: Implications to the introduction of the Muguga Cocktail vaccine for East Coast Fever

bioRxiv
East Coast Fever (ECF) is one of the most economically important tick-borne diseases of cattle in Eastern, Central, and Southern Africa, caused by the intracellular protozoan parasite Theileria parva (T. parva). This study investigated the prevalence and
Walter Muleya, Simbuwa Mulonga, V. Mbao, Kalume Moise Kasereka, Kambale Mbusa Héritier, B. Namangala, J. Salt, A. Musoke, David Kalenzi Atuhaire   +8 more
semanticscholar   +1 more source