In silico identification of Theileria parva surface proteins [PDF]
The Cell Surface, 2022 East Coast Fever is a devastating African cattle disease caused by the apicomplexan parasite, Theileria parva. Little is known about the cell surface, and few proteins have been identified.
Nitisha Gurav +3 more
doaj +6 more sources
Approaches to vaccination against Theileria parva and Theileria annulata [PDF]
Parasite Immunology, 2016 SummaryDespite having different cell tropism, the pathogenesis and immunobiology of the diseases caused by Theileria parva and Theileria annulata are remarkably similar. Live vaccines have been available for both parasites for over 40 years, but although they provide strong protection, practical disadvantages have limited their widespread application ...
W I Morrison
exaly +7 more sources
Genetic Diversity of Theileria parva and Anaplasma spp. Isolated From Ticks Collected From Kiambu County, Kenya. [PDF]
Biomed Res IntEnvironmental changes and human activities such as deforestation and expansion of agricultural land are increasing tick‐borne diseases including Anaplasmosis, Babesiosis, Ehrlichiosis, and Theileriosis. These diseases, which affect animals, can be transmitted to humans through tick bites.
Gichuki P +3 more
europepmc +2 more sources
Theileria parva in Zambia: A scoping review protocol. [PDF]
PLoS ONEObjectiveThe objective of this scoping review is to examine published and unpublished literature on Theileria parva in Zambia. It will identify the scope of available literature for research prioritization.IntroductionTheileria parva is the most lethal ...
Chishimba M Mubanga +3 more
doaj +2 more sources
Anti-parasitic benzoxaboroles are ineffective against Theileria parva in vitro [PDF]
International Journal for Parasitology: Drugs and Drug Resistance, 2023 East Coast Fever (ECF) is a disease affecting cattle in sub-Saharan Africa, caused by the tick-borne Apicomplexan pathogen Theileria parva. The disease is a major problem for cattle farmers in affected regions and there are few methods of control ...
Pieter C. Steketee +5 more
doaj +2 more sources
Molecular characterization of a synthetic neutralizing antibody targeting p67 of Theileria parva. [PDF]
Protein SciAbstract The Theileria parva sporozoite surface antigen p67 is a target of the bovine humoral immune response that generates antibodies capable of providing protection against subsequent infection. As a result, p67 has been the subject of efforts aimed at the development of an anti‐sporozoite subunit vaccine.
Miersch S +10 more
europepmc +2 more sources
Comparative transcriptional analysis identifies genes associated with the attenuation of Theileria parva infected cells after long-term in vitro culture [PDF]
Scientific ReportsAutologous administration of attenuated Theileria parva-infected cells induces immunity to T. parva in cattle. The mechanism of attenuation, however, is largely unknown. Here, we used RNA sequencing of pathogenic and attenuated T.
Elisabeth M. D. L. van der Heijden +5 more
doaj +2 more sources
Unique Mitochondrial Single Nucleotide Polymorphisms Demonstrate Resolution Potential to Discriminate Theileria parva Vaccine and Buffalo-Derived Strains [PDF]
Life, 2020 Distinct pathogenic and epidemiological features underlie different Theileria parva strains resulting in different clinical manifestations of East Coast Fever and Corridor Disease in susceptible cattle.
Micky M. Mwamuye +6 more
doaj +2 more sources
Characterization of the Theileria parva sporozoite proteome. [PDF]
Int J Parasitol, 2018 East Coast fever is a lymphoproliferative disease caused by the tick-borne protozoan parasite Theileria parva. The sporozoite stage of this parasite, harboured and released from the salivary glands of the tick Rhipicephalus appendiculatus during feeding, invades and establishes infection in bovine lymphocytes.
Nyagwange J +7 more
europepmc +4 more sources
Morbidity, mortality, and risk factors associated with Theileria parva seropositivity in a longitudinal calf study, Narok, Kenya [PDF]
Veterinary and Animal ScienceEast Coast fever (ECF), caused by Theileria parva causes devastating loss to livestock keepers in sub-Saharan Africa. A longitudinal study was carried out in Narok County to estimate the incidence and risk factors associated with Theileria parva ...
Wyckliff Ngetich +4 more
doaj +2 more sources