Absolute Quantification of the Host-To-Parasite DNA Ratio in Theileria parva-Infected Lymphocyte Cell Lines. [PDF]
Theileria parva is a tick-transmitted intracellular apicomplexan pathogen of cattle in sub-Saharan Africa that causes East Coast fever (ECF). ECF is an acute fatal disease that kills over one million cattle annually, imposing a tremendous burden on ...
Hanzel T Gotia +5 more
doaj +3 more sources
Investigation of carbohydrate-based molecules of Theileria parva parasites [PDF]
Theileria parva (Tp), the causative agent of East Coast Fever, poses a major threat to Bos taurus cattle in sub-Saharan Africa. Progress towards a stable, affordable, cross-protective subunit vaccine covering more than one major histocompatibility ...
Jeannine Kolakowski +7 more
doaj +2 more sources
Genetic Diversity and Sequence Polymorphism of Two Genes Encoding Theileria parva Antigens Recognized by CD8+ T Cells among Vaccinated and Unvaccinated Cattle in Malawi [PDF]
East Coast fever (ECF) is an acute fatal tick-borne disease of cattle caused by Theileria parva. It causes major losses in exotic and crossbreed cattle, but this could be prevented by a vaccine of T.
Elisha Chatanga +9 more
doaj +2 more sources
Prevalence and spatial distribution of Theileria parva in cattle under crop-livestock farming systems in Tororo District, Eastern Uganda [PDF]
Background Tick-borne diseases (TBDs) present a major economic burden to communities across East Africa. Farmers in East Africa must use acaracides to target ticks and prevent transmission of tick-borne diseases such as anaplasmosis, babesiosis ...
Dennis Muhanguzi +6 more
doaj +2 more sources
Seroprevalence and risk factors associated with Theileria parva infection among calves in Narok County, Kenya [PDF]
Background and Aim: East Coast fever (ECF), caused by Theileria parva, is a devastating disease that causes significant economic losses to cattle production in sub-Saharan Africa.
Wyckliff Ngetich +4 more
doaj +2 more sources
Genetic and antigenic variation of the bovine tick-borne pathogen Theileria parva in the Great Lakes region of Central Africa [PDF]
Background Theileria parva causes East Coast fever (ECF), one of the most economically important tick-borne diseases of cattle in sub-Saharan Africa. A live immunisation approach using the infection and treatment method (ITM) provides a strong long-term ...
Gaston S. Amzati +8 more
doaj +2 more sources
Capture-based enrichment of Theileria parva DNA enables full genome assembly of first buffalo-derived strain and reveals exceptional intra-specific genetic diversity. [PDF]
Theileria parva is an economically important, intracellular, tick-transmitted parasite of cattle. A live vaccine against the parasite is effective against challenge from cattle-transmissible T. parva but not against genotypes originating from the African
Nicholas C Palmateer +16 more
doaj +2 more sources
Epigenetic silencing of innate and adaptive immunity genes underlies the immune evasion cancer hallmark in Theileria-infected B-cells. [PDF]
Cancer hallmarks are characterized by wide-scale changes in gene expression programs. Pioneering studies showed how viral oncogenes target regulatory pathways, but little is known about tumorigenic mechanisms of non-viral pathogens. Theileria annulata is
Marisol Giacomini +13 more
doaj +2 more sources
The application of molecular biology techniques to analyse diversity in Theileria parva populations in Zambia [PDF]
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Theileria parva is a complex protozoan parasite causing East Coast fever in Eastern and Central Africa.
Geysen, Dirk
core +8 more sources
Genetic Diversity of Theileria parva and Anaplasma spp. Isolated From Ticks Collected From Kiambu County, Kenya. [PDF]
Environmental changes and human activities such as deforestation and expansion of agricultural land are increasing tick‐borne diseases including Anaplasmosis, Babesiosis, Ehrlichiosis, and Theileriosis. These diseases, which affect animals, can be transmitted to humans through tick bites.
Gichuki P +3 more
europepmc +2 more sources

