Population genetic analysis and sub-structuring of
Parasites & Vectors, 2012 Background Theileriosis, caused by Theileria parva, is an economically important disease in Africa. It is a major constraint to the development of the livestock industry in some parts of eastern, central and southern Africa.
Muleya Walter +8 more
doaj +3 more sources
Absolute Quantification of the Host-To-Parasite DNA Ratio in Theileria parva-Infected Lymphocyte Cell Lines. [PDF]
PLoS ONE, 2016 Theileria parva is a tick-transmitted intracellular apicomplexan pathogen of cattle in sub-Saharan Africa that causes East Coast fever (ECF). ECF is an acute fatal disease that kills over one million cattle annually, imposing a tremendous burden on ...
Hanzel T Gotia +5 more
doaj +3 more sources
An Improved Theileria parva Sporozoite Seroneutralization Assay for the Identification of East Coast Fever Immune Correlates [PDF]
AntibodiesBackground: Immune correlates of protection are ideal tools to predict treatment or vaccine efficacy. However, the accuracy of the immune correlate and the capability to robustly predict the outcome of a vaccine candidate are determined by the ...
Hannah Chege +10 more
doaj +2 more sources
South African Buffalo-Derived Theileria parva Is Distinct From Other Buffalo and Cattle-Derived T. parva [PDF]
Frontiers in Genetics, 2021 Theileria parva is a protozoan parasite transmitted by the brown-eared ticks, Rhipicephalus appendiculatus and Rhipicephalus zambeziensis. Buffaloes are the parasite’s ancestral host, with cattle being the most recent host.
Boitumelo B. Maboko +12 more
doaj +2 more sources
Prevalence of tick-transmitted pathogens in cattle reveals that Theileria parva, Babesia bigemina and Anaplasma marginale are endemic in Burundi [PDF]
Parasites & Vectors, 2021 Background Tick-borne diseases (TBDs) constitute a major constraint for livestock development in sub-Saharan Africa, with East Coast fever (ECF) being the most devastating TBD of cattle. However, in Burundi, detailed information is lacking on the current
Lionel Nyabongo +8 more
doaj +2 more sources
Antigenic Diversity in Theileria parva Populations From Sympatric Cattle and African Buffalo Analyzed Using Long Read Sequencing [PDF]
Frontiers in Genetics, 2021 East Coast fever (ECF) in cattle is caused by the Apicomplexan protozoan parasite Theileria parva, transmitted by the three-host tick Rhipicephalus appendiculatus. The African buffalo (Syncerus caffer) is the natural host for T. parva but does not suffer
Fiona K. Allan +15 more
doaj +2 more sources
Investigation of carbohydrate-based molecules of Theileria parva parasites [PDF]
Frontiers in Veterinary ScienceTheileria parva (Tp), the causative agent of East Coast Fever, poses a major threat to Bos taurus cattle in sub-Saharan Africa. Progress towards a stable, affordable, cross-protective subunit vaccine covering more than one major histocompatibility ...
Jeannine Kolakowski +7 more
doaj +2 more sources
Prevalence and spatial distribution of Theileria parva in cattle under crop-livestock farming systems in Tororo District, Eastern Uganda [PDF]
Parasites & Vectors, 2014 Background Tick-borne diseases (TBDs) present a major economic burden to communities across East Africa. Farmers in East Africa must use acaracides to target ticks and prevent transmission of tick-borne diseases such as anaplasmosis, babesiosis ...
Dennis Muhanguzi +6 more
doaj +2 more sources
Genetic Diversity and Sequence Polymorphism of Two Genes Encoding Theileria parva Antigens Recognized by CD8+ T Cells among Vaccinated and Unvaccinated Cattle in Malawi [PDF]
Pathogens, 2020 East Coast fever (ECF) is an acute fatal tick-borne disease of cattle caused by Theileria parva. It causes major losses in exotic and crossbreed cattle, but this could be prevented by a vaccine of T.
Elisha Chatanga +9 more
doaj +2 more sources
TparvaDB: a database to support Theileria parva vaccine development [PDF]
Database, 2011 We describe the development of TparvaDB, a comprehensive resource to facilitate research towards development of an East Coast fever vaccine, by providing an integrated user-friendly database of all genome and related data currently available for Theileria parva. TparvaDB is based on the Generic Model Organism Database (GMOD) platform.
Paul Visendi +5 more
openaire +5 more sources