Approaches to vaccination against Theileria parva and Theileria annulata [PDF]
Parasite Immunology, 2016 SummaryDespite having different cell tropism, the pathogenesis and immunobiology of the diseases caused by Theileria parva and Theileria annulata are remarkably similar. Live vaccines have been available for both parasites for over 40 years, but although they provide strong protection, practical disadvantages have limited their widespread application ...
Nene V, Morrison WI.
exaly +7 more sources
Investigation of carbohydrate-based molecules of Theileria parva parasites [PDF]
Frontiers in Veterinary ScienceTheileria parva (Tp), the causative agent of East Coast Fever, poses a major threat to Bos taurus cattle in sub-Saharan Africa. Progress towards a stable, affordable, cross-protective subunit vaccine covering more than one major histocompatibility ...
Jeannine Kolakowski +7 more
doaj +2 more sources
Genetic Diversity and Sequence Polymorphism of Two Genes Encoding Theileria parva Antigens Recognized by CD8+ T Cells among Vaccinated and Unvaccinated Cattle in Malawi [PDF]
Pathogens, 2020 East Coast fever (ECF) is an acute fatal tick-borne disease of cattle caused by Theileria parva. It causes major losses in exotic and crossbreed cattle, but this could be prevented by a vaccine of T.
Elisha Chatanga +9 more
doaj +2 more sources
Seroprevalence and risk factors associated with Theileria parva infection among calves in Narok County, Kenya [PDF]
Veterinary WorldBackground and Aim: East Coast fever (ECF), caused by Theileria parva, is a devastating disease that causes significant economic losses to cattle production in sub-Saharan Africa.
Wyckliff Ngetich +4 more
doaj +2 more sources
Genetic and antigenic variation of the bovine tick-borne pathogen Theileria parva in the Great Lakes region of Central Africa [PDF]
Parasites & Vectors, 2019 Background Theileria parva causes East Coast fever (ECF), one of the most economically important tick-borne diseases of cattle in sub-Saharan Africa. A live immunisation approach using the infection and treatment method (ITM) provides a strong long-term ...
Gaston S. Amzati +8 more
doaj +2 more sources
Capture-based enrichment of Theileria parva DNA enables full genome assembly of first buffalo-derived strain and reveals exceptional intra-specific genetic diversity. [PDF]
PLoS Neglected Tropical Diseases, 2020 Theileria parva is an economically important, intracellular, tick-transmitted parasite of cattle. A live vaccine against the parasite is effective against challenge from cattle-transmissible T. parva but not against genotypes originating from the African
Nicholas C Palmateer +16 more
doaj +2 more sources
First detection of Theileria parva in cattle from Cameroon in the absence of the main tick vector Rhipicephalus appendiculatus [PDF]
Transboundary and Emerging Diseases, 2020 David Odongo +2 more
exaly +2 more sources
Characterization of the Theileria parva sporozoite proteome. [PDF]
Int J Parasitol, 2018 East Coast fever is a lymphoproliferative disease caused by the tick-borne protozoan parasite Theileria parva. The sporozoite stage of this parasite, harboured and released from the salivary glands of the tick Rhipicephalus appendiculatus during feeding, invades and establishes infection in bovine lymphocytes.
Nyagwange J +7 more
europepmc +4 more sources
Evaluation of a real-time PCR test for the detection and discrimination of theileria species in the African buffalo (Syncerus caffer). [PDF]
PLoS ONE, 2013 A quantitative real-time PCR (qPCR) assay based on the cox III gene was evaluated for the simultaneous detection and discrimination of Theileria species in buffalo and cattle blood samples from South Africa and Mozambique using melting curve analysis ...
Mamohale E Chaisi +5 more
doaj +1 more source
Economics of East Coast fever: a literature review
Frontiers in Veterinary Science, 2023 East Coast fever (ECF) is a cattle disease caused by a protozoan parasite called Theileria parva (T. parva). Theileria parva is transmitted among cattle by ticks.
Aditi A. Surve +6 more
doaj +1 more source