Results 31 to 40 of about 3,404 (205)

Survival of Theileria parva in its nymphal tick vector Rhipicephalus appendiculatus under laboratory and quasi natural conditions [PDF]

, 2003
Groups of nymphal Rhipicephalus appendiculatus Muguga, having a mean of 1 or 9 Theileria parva Muguga-infected salivary gland acini per tick, were kept under quasi-natural conditions at an altitude of 1950 m or 20°C at a relative humidity of 85% in the ...
Young, A. S., Medley, Graham, Ochanda, Horace   +2 more
core   +1 more source

Genome analysis of Theileria parva

Parasitology Today, 1993
Recent technological developments in the field of genome analyses have advanced our knowledge of the structures of prokaryotic and eukoryotic genomes. Examples of these range from small bacterial genomes, such as Escherichia coli, to the more complex genomes of Caenorhabditis elegans, Drosophila, humans and mouse.
Morzaria, S.P., Young, J.R.
openaire   +3 more sources

Cloned Theileria parva produces lesser infections in ticks compared to uncloned T. parva despite similar infections in cattle : research communication

Onderstepoort Journal of Veterinary Research, 2006
Experimental transmissions of cloned Theileria parva in cattle with Rhipicephalus appendiculatus ticks were compared to transmissions with uncloned T.
A.R. Walker, F. Katzer, D. Ngugi, D. McKeever   +3 more
doaj   +1 more source

The African buffalo parasite Theileria. sp. (buffalo) can infect and immortalize cattle leukocytes and encodes divergent orthologues of Theileria parva antigen genes

International Journal for Parasitology: Parasites and Wildlife, 2015
African Cape buffalo (Syncerus caffer) is the wildlife reservoir of multiple species within the apicomplexan protozoan genus Theileria, including Theileria parva which causes East coast fever in cattle.
R.P. Bishop, J.D. Hemmink, W.I. Morrison, W. Weir, P.G. Toye, T. Sitt, P.R. Spooner, A.J. Musoke, R.A. Skilton, D.O. Odongo   +9 more
doaj   +1 more source

Comparative Genome Analysis of Three Eukaryotic Parasites with Differing Abilities To Transform Leukocytes Reveals Key Mediators of Theileria-Induced Leukocyte Transformation

mBio, 2012
We sequenced the genome of Theileria orientalis, a tick-borne apicomplexan protozoan parasite of cattle. The focus of this study was a comparative genome analysis of T. orientalis relative to other highly pathogenic Theileria species, T.
Kyoko Hayashida, Yuichiro Hara, Takashi Abe, Chisato Yamasaki, Atsushi Toyoda, Takehide Kosuge, Yutaka Suzuki, Yoshiharu Sato, Shuichi Kawashima, Toshiaki Katayama, Hiroyuki Wakaguri, Noboru Inoue, Keiichi Homma, Masahito Tada-Umezaki, Yukio Yagi, Yasuyuki Fujii, Takuya Habara, Minoru Kanehisa, Hidemi Watanabe, Kimihito Ito, Takashi Gojobori, Hideaki Sugawara, Tadashi Imanishi, William Weir, Malcolm Gardner, Arnab Pain, Brian Shiels, Masahira Hattori, Vishvanath Nene, Chihiro Sugimoto   +29 more
doaj   +1 more source

Investigations into the carrier-state of Theileria sp. (buffalo) in cattle

International Journal for Parasitology: Parasites and Wildlife, 2020
The Theileria are apicomplexan parasites transmitted by ticks to vertebrate hosts. Most Theileria species exhibit some form of host or vector specificity, since under endemic conditions only a limited number of tick species act as vectors and not all ...
Ronel Pienaar, P. Christo Troskie, Antoinette I. Josemans, Fred T. Potgieter, Boitumelo B. Maboko, Abdalla A. Latif, Ben J. Mans   +6 more
doaj   +1 more source

High-resolution genotyping and mapping of recombination and gene conversion in the protozoan Theileria parva using whole genome sequencing [PDF]

, 2012
BACKGROUND: Theileria parva is a tick-borne protozoan parasite, which causes East Coast Fever, a disease of cattle in sub-Saharan Africa. Like Plasmodium falciparum, the parasite undergoes a transient diploid life-cycle stage in the gut of the arthropod ...
Spooner Paul R, Ulrich Certa, Pelle, R., Richard P Bishop, Ebeling, M., Pelle Roger, Lucy Poveda, Roger Pelle, Küng, Erich, Morzaria, S., Henson, Sonal, Morzaria, S.P., Erich Küng, Bishop, Richard P., Daubenberger, C.A., Daubenberger, Claudia A., Certa, U., Spooner, Paul R, Poveda, Lucy, Paul R Spooner, Poveda, L., Ebeling, Martin, Certa, Ulrich, Claudia A Daubenberger, Spooner, P.R., Weihong Qi, Sonal Henson, Bishop Richard P, Spooner, Paul R., Certa Ulrich, Henson Sonal, Henson, S., Morzaria Subhash, Qi Weihong, Poveda Lucy, Subhash Morzaria, Bishop, R. P., Spooner, P. R., Kung, E., Pelle, Roger, Ebeling Martin, Küng Erich, Daubenberger Claudia A, Morzaria, Subhash, Daubenberger, C. A., Bishop, Richard P, Martin Ebeling, Qi, W., Qi, Weihong, Daubenberger, Claudia A   +49 more
core   +1 more source

The genomes of three stocks comprising the most widely utilized live sporozoite Theileria parva vaccine exhibit very different degrees and patterns of sequence divergence [PDF]

, 2015
There are no commercially available vaccines against human protozoan parasitic diseases, despite the success of vaccination-induced long-term protection against infectious diseases.
Sonal Henson, Kyle Tretina, Thomas Njoroge, Tretina, Kyle, David Odongo, Silva, Joana C., Norling, Martin, Njoroge, Thomas, Roger Pelle, Bongcam-Rudloff, Erik, Henson, Sonal, Drábek, Elliott F, Elliott F. Drábek, Stephen Mwaura, Bishop, Richard P., Daubenberger, Claudia A., Richard P. Bishop, Pelle, Roger, Erik Bongcam-Rudloff, Martin Norling, Joana C. Silva, Odongo, David, Bishop, Richard P, Claudia A. Daubenberger, Drábek, Elliott F., Mwaura, Stephen, Qi, Weihong, Daubenberger, Claudia A, Silva, Joana C, Weihong Qi   +29 more
core   +1 more source

A Sporozoite-based vaccine for Theileria parva

Parasitology Today, 1993
East Coast fever, which is caused by Theileria parva infection in cattle, is of major economic importance in eastern and central Africa. Until recently, the only available method of immunization against East Coast fever was the infection with live sporozoites and simultaneous treatment with a long-acting oxytetracycline.
Musoke, A.J., Nene, Vishvanath, Morzaria, S.P.   +2 more
openaire   +3 more sources

Leveraging the Medicines for Malaria Venture malaria and pathogen boxes to discover chemical inhibitors of East Coast fever

International Journal for Parasitology: Drugs and Drug Resistance, 2019
Chemotherapy of East Coast fever, a lymphoproliferative cancer-like disease of cattle causing significant economic losses in Africa, is largely dependent on the use of buparvaquone, a drug that was developed in the late 1980's.
James Nyagwange, Elias Awino, Edwin Tijhaar, Nicholas Svitek, Roger Pelle, Vishvanath Nene   +5 more
doaj   +1 more source