Results 31 to 40 of about 14,799 (201)

Cloned Theileria parva produces lesser infections in ticks compared to uncloned T. parva despite similar infections in cattle : research communication

Onderstepoort Journal of Veterinary Research, 2006
Experimental transmissions of cloned Theileria parva in cattle with Rhipicephalus appendiculatus ticks were compared to transmissions with uncloned T.
A.R. Walker, F. Katzer, D. Ngugi, D. McKeever   +3 more
doaj   +1 more source

The African buffalo parasite Theileria. sp. (buffalo) can infect and immortalize cattle leukocytes and encodes divergent orthologues of Theileria parva antigen genes

International Journal for Parasitology: Parasites and Wildlife, 2015
African Cape buffalo (Syncerus caffer) is the wildlife reservoir of multiple species within the apicomplexan protozoan genus Theileria, including Theileria parva which causes East coast fever in cattle.
R.P. Bishop, J.D. Hemmink, W.I. Morrison, W. Weir, P.G. Toye, T. Sitt, P.R. Spooner, A.J. Musoke, R.A. Skilton, D.O. Odongo   +9 more
doaj   +1 more source

CD8+ T-cell responses to Theileria parva are preferentially directed to a single dominant antigen:Implications for parasite strain-specific immunity [PDF]

, 2009
Although immunodominance of CD8(+) T-cell responses is a well-recognised feature of viral infections, its role in responses to more antigenically complex pathogens is less clear.
Connelley, T., Burrells, A, W. Ivan Morrison, Declan J. McKeever, Connelley, Timothy, Taracha, Evans L., Connelly, T, McKeever, DJ, Morrison, WI, Simon P. Graham, Burrells, A., MacHugh, ND, McKeever, D J, Taracha, E.L.N., Niall D. MacHugh, Roger Pelle, Ellis, SA, McKeever, Declan J., MacHugh, N D, Connelley, T, Evans L. Taracha, Ellis, S A, Graham, SP, Pelle, Roger, Ellis, Shirley A., MacHugh, Niall D., Formisano, Principia, Formisano, P, Principia Formisano, Taracha, EL, Ellis, S.A., Shirley A. Ellis, Taracha, E L, Alison Burrells, Pelle, R, IAH, Graham, Simon P., Graham, S P, Timothy Connelley, Formisano, P., Royal (Dick) School of Veterinary Studies, ILRI, Morrison, W. Ivan, Burrells, Alison, Graham, S.P.   +44 more
core   +1 more source

Comparative Genome Analysis of Three Eukaryotic Parasites with Differing Abilities To Transform Leukocytes Reveals Key Mediators of Theileria-Induced Leukocyte Transformation

mBio, 2012
We sequenced the genome of Theileria orientalis, a tick-borne apicomplexan protozoan parasite of cattle. The focus of this study was a comparative genome analysis of T. orientalis relative to other highly pathogenic Theileria species, T.
Kyoko Hayashida, Yuichiro Hara, Takashi Abe, Chisato Yamasaki, Atsushi Toyoda, Takehide Kosuge, Yutaka Suzuki, Yoshiharu Sato, Shuichi Kawashima, Toshiaki Katayama, Hiroyuki Wakaguri, Noboru Inoue, Keiichi Homma, Masahito Tada-Umezaki, Yukio Yagi, Yasuyuki Fujii, Takuya Habara, Minoru Kanehisa, Hidemi Watanabe, Kimihito Ito, Takashi Gojobori, Hideaki Sugawara, Tadashi Imanishi, William Weir, Malcolm Gardner, Arnab Pain, Brian Shiels, Masahira Hattori, Vishvanath Nene, Chihiro Sugimoto   +29 more
doaj   +1 more source

Investigations into the carrier-state of Theileria sp. (buffalo) in cattle

International Journal for Parasitology: Parasites and Wildlife, 2020
The Theileria are apicomplexan parasites transmitted by ticks to vertebrate hosts. Most Theileria species exhibit some form of host or vector specificity, since under endemic conditions only a limited number of tick species act as vectors and not all ...
Ronel Pienaar, P. Christo Troskie, Antoinette I. Josemans, Fred T. Potgieter, Boitumelo B. Maboko, Abdalla A. Latif, Ben J. Mans   +6 more
doaj   +1 more source

A Sporozoite-based vaccine for Theileria parva

Parasitology Today, 1993
East Coast fever, which is caused by Theileria parva infection in cattle, is of major economic importance in eastern and central Africa. Until recently, the only available method of immunization against East Coast fever was the infection with live sporozoites and simultaneous treatment with a long-acting oxytetracycline.
Musoke, A.J., Nene, Vishvanath, Morzaria, S.P.   +2 more
openaire   +3 more sources

Population genetic analysis and sub-structuring of Theileria parva in the northern and eastern parts of Zambia

Parasites & Vectors, 2012
Background Theileriosis, caused by Theileria parva, is an economically important disease in Africa. It is a major constraint to the development of the livestock industry in some parts of eastern, central and southern Africa.
Muleya Walter, Namangala Boniface, Simuunza Martin, Nakao Ryo, Inoue Noboru, Kimura Takashi, Ito Kimihito, Sugimoto Chihiro, Sawa Hirofumi   +8 more
doaj   +1 more source

Leveraging the Medicines for Malaria Venture malaria and pathogen boxes to discover chemical inhibitors of East Coast fever

International Journal for Parasitology: Drugs and Drug Resistance, 2019
Chemotherapy of East Coast fever, a lymphoproliferative cancer-like disease of cattle causing significant economic losses in Africa, is largely dependent on the use of buparvaquone, a drug that was developed in the late 1980's.
James Nyagwange, Elias Awino, Edwin Tijhaar, Nicholas Svitek, Roger Pelle, Vishvanath Nene   +5 more
doaj   +1 more source

Vaccines against Theileria parva

Annals of the New York Academy of Sciences, 2000
Abstract: Bovine theileriosis caused by Theileria parva continues to be a major economic problem in many parts of Eastern, Southern, and Central Africa. Due to the unsustainable nature of the present control method‐using toxic acaricides to kill ticks‐alternative control methods are being sought.
Morzaria, S.P., Nene, Vishvanath, Bishop, Richard P., Musoke, A.J.   +3 more
openaire   +3 more sources

Survival of Theileria parva in its nymphal tick vector Rhipicephalus appendiculatus under laboratory and quasi natural conditions [PDF]

, 2003
Groups of nymphal Rhipicephalus appendiculatus Muguga, having a mean of 1 or 9 Theileria parva Muguga-infected salivary gland acini per tick, were kept under quasi-natural conditions at an altitude of 1950 m or 20°C at a relative humidity of 85% in the ...
Young, A. S., Medley, Graham, Ochanda, Horace   +2 more
core   +1 more source