Results 31 to 40 of about 635,246 (293)
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Introduction: Diet related diseases are diseases in human body for a long period of time that is not dangerous and it can be preventable. This diet related diseases occur due to poor eating habits.
Yogesraj Selvamoney +1 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Large language models for closed-library multi-document query, test generation, and evaluation
IntroductionLearning complex, detailed, and evolving knowledge is a challenge in multiple technical professions. Relevant source knowledge is contained within many large documents and information sources with frequent updates to these documents ...
Claire Randolph +2 more
doaj +1 more source
Pembuatan Aplikasi Mobile Learning sebagai Sarana Pembelajaran di Lingkungan Universitas Diponegoro
Mobile learning is the intersection of Mobile Computing and E-Learning that provides the resources that can be accessed from anywhere, a powerful search system capabilities, rich interaction, full support for effective learning and assessment based on ...
Afandi Nur Aziz Thohari +2 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
NETME: on-the-fly knowledge network construction from biomedical literature
Background The rapidly increasing biological literature is a key resource to automatically extract and gain knowledge concerning biological elements and their relations.
Alessandro Muscolino +9 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Knowledge Patterns and Knowledge Refactorings for Increasing the Quality of Knowledge
S.281-328Knowledge management is a relatively young discipline. It has accumulated a valuable body-of-knowledge on how to structure and represent knowledge, or how to design socio-technical knowledge management systems.
Rech, J. +4 more
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