Results 61 to 70 of about 239,945 (258)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Easy Language research [PDF]

open access: yesNordic Journal of Linguistics, 2021
Ulla Vanhatalo   +2 more
openaire   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Visual support in easy language: The impact of images on comprehension, perceived difficulty and eye movements

open access: yesLanguage and Cognition
Easy Language (EL) presents information in a simplified way and benefits people who have difficulty understanding standard language. The present study evaluates the effects of visual support inclusion, as it is a recurring recommendation in EL guidelines.
Mariona González-Sordé   +3 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Artificial intelligence and natural language processing for easy-to-read texts

open access: yesRevista de Llengua i Dret - Journal of Language and Law
Access to information is a fundamental human right that contributes to freedom of expression and self-determination. However, information availability alone is not enough: the way in which information is expressed and presented on paper or in digital ...
Horacio Saggion
doaj   +1 more source

Easy Language in Italy

open access: yes, 2021
This is a chapter is about both the past and the present of Easy Italian in the European context. It takes its reader on a tour of Italy, opening windows and peeking into dif¬ferent aspects of the way Easy Italian has been (or has not been) implemented in diverse sectors, and reveals how Easy Language and accessible communication are realized in a wide
openaire   +1 more source

Signbank 2.0 of Sign Languages: Easy to Administer, Easy to Use, Easy to Share

open access: yesProceedings of the Language Resources and Evaluation Conference
Ronice Muller de Quadros, Christian Rathmann, Peter Zalán Romanek, Francisco Fernandes, and Sther Condé. 2024. Signbank 2.0 of Sign Languages: Easy to Administer, Easy to Use, Easy to Share. In Proceedings of the LREC-COLING 2024 11th Workshop on the Representation and Processing of Sign Languages: Evaluation of Sign Language Resources, pages 302–314 ...
Quadros, Ronice Müller de   +4 more
openaire   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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