Results 111 to 120 of about 772,644 (300)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

DHA, Eat or Not Eat？

International Journal of Psychiatry and Neurology, 2017
目的：目前市场上出售的保健品种类繁多，我们如何选择一种无副作用还能对疾病起到预防作用的保健品呢？DHA (ω-3：7，10，13，16，19-二十二碳六烯酸)作为一种多不饱和脂肪酸，能够通过血脑屏障，是大脑皮层神经元细胞膜的形成的重要原料；改善人类认知功能，减轻阿尔茨海默病和抑郁症的发生；方法：本文把近年来国外对DHA的研究情况作了系统综述。结果与结论：DHA的开发利用己受到世界各国的关注和重视。DHA能够预防和改善精神疾病和神经退行性病变。选择DHA作为一种保健品，不失为一种明智的选择。 Various health products are sold on the market at present. How can we choose a health product which has no
openaire   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Encouraging healthy eating behaviours through healthy eating environments. Case of Durham University [PDF]

, 2011
The aim of the study was to perform a formative research by exploring, describing and evaluating at the same time on various factors that influence eating behaviours on campus.
VELINOVA, ILIANA,DONEVA
core  

Normative body dissatisfaction and eating psychopathology in teenage girls: the impact of inflexible eating rules

, 2015
Adolescence has been considered a critical time for the development of body image-related difficulties and disordered eating behaviours, especially in females.
Ferreira, Cláudia,, Duarte, Cristiana,, Ferreira, Cláudia, Trindade, Inês A.,, Pinto-Gouveia, José,, Pinto-Gouveia, José, Duarte, Cristiana, Trindade, Inês A.   +7 more
core   +1 more source

Ethical implications of defining longstanding anorexia nervosa

Journal of Eating Disorders
The label severe and enduring anorexia nervosa (SE-AN) is widely used in the literature on longstanding anorexia nervosa (AN). However, the process of constructing the criteria and the use of the label SE-AN has ethical implications that have not been ...
Marthe M. Voswinkel, Simone M. Hanegraaff, Suzanne H.W. Mares, Elke Wezenberg, Johannes J.M. van Delden, Annemarie A. van Elburg   +5 more
doaj   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Body image flexibility and embodiment in eating disorders: a mixed-methods approach combining network analysis and pilot exposure protocol

Journal of Eating Disorders
Objective Body image (BI) disturbances are central to the psychopathology of eating disorders (EDs), where body dissatisfaction and disembodiment often co-occur, exacerbating negative body image experiences. We aimed to examine body image flexibility and
Paolo Meneguzzo, Chiara Cazzola, Francesca Buscaglia, Anna Pillan, Filippo Pettenuzzo, Patrizia Todisco   +5 more
doaj   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

The development and validation of a shortened version of the Eating Disorder Examination Questionnaire (EDE-Q) [PDF]

, 2014
Aims: The aim of this study was to develop and validate a short version of the Eating Disorder Examination Questionnaire (EDE-Q) for sessional outcome assessment, which is sensitive to clinical change. Method: A principal component analysis was conducted
Gideon, N
core