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Food has many functions and meanings. It is, indeed, necessary for our nourishment but since human beings are related to one another, food is a symbolic form of communication, too. It can also play other roles. It can be a ritual, it can transmit values, norms of conduct and beliefs, it can trigger nostalgic childhood memories or, by recreating lost ...
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Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
Covid had a profound impact on services for eating disorders because of the huge increase in demand. Nevertheless, services quickly adopted a virtual form of working. This rapid change in prevalence was attributed to a number of factors, including a general increase in fear and fragmented social functioning, with a specific accentuation of higher risk ...
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Disordered Eating in Collegiate Athletes: Prevalence and Relationships with Body Composition [PDF]
Performance pressures and emphasis on body weight and shape put collegiate athletes at risk for disordered eating. If not identified early, disordered eating behaviors could develop into a clinical eating disorder.
Apsey, Sofia
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Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Physical appearance perfectionism explains variance in eating disorder symptoms above general perfectionism [PDF]
Physical appearance perfectionism is a domain-specific form of perfectionism comprising two components: hope for perfection and worry about imperfection (Yang & Stoeber, 2012).
Bardone-Cone+47 more
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TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
To eat or not to eat: The NICE way.
Seventh international symposium on preventive oncology and intervention strategies brought several scientists and physicians together in a French city, Nice from 7-10th February 2004.
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The Link Between Dissociation, Eating Disorders, and Self-Harm [PDF]
Many researchers and psychological professionals believe that there is a link between eating disorders and self-harm, though this has been less widely researched than other correlations such as that between eating disorders and substance abuse.
Zimmerman, Amy A
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Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source