Results 141 to 150 of about 10,694 (250)

Functional Suppression of SCAP Triggers Endoplasmic Reticulum Stress‐Dependent Ferroptosis by Impairing Cholesterol Metabolism in Gastric Cancer

Advanced Science, EarlyView.
This study reveals a novel GC therapy targeting cholesterol homeostasis. Inhibiting the SCAP sterol‐sensing domain causes lethal ER stress via cholesterol accumulation, paradoxically forcing continuous synthesis that triggers ferroptosis. The findings link sterol sensing, metabolic dysregulation, and ferroptosis, establishing an anti‐cancer paradigm ...
Qianqian Xu, Guangzhao Pan, Lele Zhang, Xiangliu Chen, Kui Zhang, Yang Lu, Zibo Duan, Aiping Chen, Hailong Shen, Yuxi Zhang, Xiaowu Dong, Jinzhou Huang, Xing Huang, Kai Miao, Qian Hua, Fangfang Tao, Weidong Zhang, Jiang‐Jiang Qin   +17 more
wiley   +1 more source

Views of people with disordered eating on current and alternative out-of-home calorie labelling policies in England: a mixed-methods survey. [PDF]

BMJ Public Health
Trompeter N, Nadarajah A, Sharpe H, Duffy F, Maloney E, Nicholls D, Serpell L, Schmidt U, Jewell T.   +8 more
europepmc   +1 more source

Deciphering Intricacies in Directional CO2 Conversion From Electrolysis to CO2 Batteries

Advanced Energy Materials, EarlyView.
This review will delve into the inherent connections and distinctions of CO2‐directed conversion in ECO2RR and CO2 batteries, in terms of product types, catalyst selection, catalytic mechanisms, and electrochemical performances, while proposing a benchmarking framework for the evaluation of CO2 batteries and innovative CO2 battery configurations for ...
Changfan Xu, Huaping Zhao, Lizhuang Chen, Weidong Shi, Guosheng Shao, Yong Lei   +5 more
wiley   +1 more source

NICE guidance, eating disorders and older people. [PDF]

BJPsych Open
Heywood-Everett S, Shirley LJ, Aqsa N, Fitzgerald K, Horsfall R.   +4 more
europepmc   +1 more source

A Highly Hydrophilic Air Electrode With Water‐Induced Surface Reconstruction for Efficient Reversible Protonic Ceramic Cell at Low Water Partial Pressures

Advanced Energy Materials, EarlyView.
This work demonstrates a new strategy for reversible protonic ceramic cells (R‐PCCs). By developing highly hydrophilic oxides, efficient operation is achieved under low water vapor pressures while maintaining high performance and stability. This approach addresses the challenge of hydrogen production in freshwater‐scarce regions.
Nai Shi, Yun Xie, Xueyu Hu, Junji Hyodo, Chun‐Kuo Peng, Gaopeng Zhou, Hanwen Liu, Bingbing Qiu, Daqin Guan, Jiayi Tang, Yan‐Gu Lin, Ranran Peng, Moses Oludayo Tadé, Meilin Liu, Yoshihiro Yamazaki, Zongping Shao   +15 more
wiley   +1 more source

Dictionary‐based weak‐form training for noise‐robust series hybrid models with multiplicative unknowns

AIChE Journal, EarlyView.
ABSTRACT Hybrid modeling combines first‐principles equations with a data‐driven subcomponent. Training for the data‐driven part is sensitive to measurement noise when training targets are constructed using pointwise time derivatives. Beyond differentiation errors, hybrid models involve solving an inverse problem to estimate the data‐driven term, which ...
Hangjun Cho, Akshay Kudva, Parth Shah, Dongheon Lee, Joseph Sang‐Il Kwon   +4 more
wiley   +1 more source

A scoping review of eating disorder symptoms and mental health during the postpartum period: predictors, course, and consequences for mothers and infants. [PDF]

J Eat Disord
Pearsall MS, Lin WC, O'Shea NG.
europepmc   +1 more source

Automated generative process synthesis via transformer‐based dual‐loop simulation and optimization

AIChE Journal, EarlyView.
Abstract This study presents a novel framework for automated generative process synthesis, addressing the complexity of simultaneously optimizing discrete topologies and continuous operating variables. To overcome conventional superstructure limitations, we propose a dual‐loop architecture integrating generative transformers with rigorous process ...
Yeong Woo Son, Chan Kim, Ji Hun Pak, Hain Lee, Jong Min Lee   +4 more
wiley   +1 more source

Efficacy of Dialectical Behavior Therapy (DBT) and DBT-Informed Interventions for Binge Eating in Adolescents: A Systematic Review. [PDF]

Cureus
Khormi MA, Abu Hayyah AE, Aljohani WF, Mahasi KA, Shok SH, Bajobeir RA, Sumayli RA, Alahmadi WM, Alsini AA, Alharthi OF, Alsubaie SM, Homoq MA.   +11 more
europepmc   +1 more source

Large Language Model in Materials Science: Roles, Challenges, and Strategic Outlook

Advanced Intelligent Discovery, EarlyView.
Large language models (LLMs) are reshaping materials science. Acting as Oracle, Surrogate, Quant, and Arbiter, they now extract knowledge, predict properties, gauge risk, and steer decisions within a traceable loop. Overcoming data heterogeneity, hallucinations, and poor interpretability demands domain‐adapted models, cross‐modal data standards, and ...
Jinglan Zhang, Xinyi Chen, Xu Ye, Yulin Yang, Bin Ai   +4 more
wiley   +1 more source