Results 41 to 50 of about 218,517 (269)

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Clinical and scientific review of severe and enduring anorexia nervosa in intensive care settings: introducing an innovative treatment paradigm

Journal of Eating Disorders
Background Anorexia nervosa is a serious and potentially lethal psychiatric disorder. Furthermore, there is significant evidence that some individuals develop a very long-standing form of the illness that requires a variety of different treatment ...
Joseph A Wonderlich, Dorian R Dodd, Cindy Sondag, Michelle Jorgensen, Candice Blumhardt, Alexandra N Evanson, Casey Bjoralt, Stephen A Wonderlich   +7 more
doaj   +1 more source

Online cognitive behavioral therapy enhanced for binge eating disorder: study protocol for a randomized controlled trial

BMC Psychiatry, 2020
Background Binge eating disorder is characterized by recurrent episodes of binge eating accompanied by a sense of lack of control. Of the different treatments available, Cognitive Behavioral Therapy-Enhanced and guided self-help treatment are recommended.
Elske van den Berg, Bernou Melisse, Jitske Koenders, Margo de Jonge, Matthijs Blankers, Edwin de Beurs, Jack Dekker   +6 more
doaj   +1 more source

Personality characteristics and medical impact of stimulant laxative abuse in eating disorder patients—a pilot study

Journal of Eating Disorders, 2021
Background Stimulant laxative abuse as a purging behavior can be profound in those with eating disorders. However, the psychopathology leading to stimulant laxative abuse is poorly understood.
Dennis Gibson, Jodie Benabe, Ashlie Watters, Judy Oakes, Philip S. Mehler   +4 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Models of care for eating disorders: findings from a rapid review

Journal of Eating Disorders, 2022
Background Delayed diagnosis, gaps in services and subsequent delays in specialist care and treatment lead to poorer health outcomes for individuals with eating disorders (EDs) and drive significant government healthcare expenditure.
Melissa J. Pehlivan, Jane Miskovic-Wheatley, Anvi Le, Danielle Maloney, National Eating Disorders Research Consortium, Stephen Touyz, Sarah Maguire   +6 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Peer mentoring for eating disorders: evaluation of a pilot program

Pilot and Feasibility Studies, 2018
Background Eating disorders are serious psychiatric illnesses that are often associated with poor quality of life and low long-term recovery rates. Peer mentor programs have been found to improve psychiatric symptoms and quality of life in other mental ...
Jennifer Beveridge, Andrea Phillipou, Kelly Edwards, Alice Hobday, Krissy Hilton, Cathy Wyett, Anna Saw, Georgia Graham, David Castle, Leah Brennan, Philippa Harrison, Rebecca de Gier, Narelle Warren, Freya Hanly, Benjamin Torrens-Witherow, J. Richard Newton, Steering group committee   +16 more
doaj   +1 more source

Moving online: young people and parents’ experiences of adolescent eating disorder day programme treatment during the COVID-19 pandemic

Journal of Eating Disorders, 2021
Plain English summary This study examined the experiences of young people and their parents who attended an intensive day treatment programme for anorexia online during the COVID-19 pandemic. Online questionnaires were completed by 14 patients aged 12–18 
Phillipa Louise Brothwood, Julian Baudinet, Catherine S. Stewart, Mima Simic   +3 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source