Results 51 to 60 of about 1,778,260 (259)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Implementation of enhanced cognitive behaviour therapy (CBT-E) for adults with anorexia nervosa in an outpatient eating-disorder unit at a public hospital

Journal of Eating Disorders, 2018
Background Anorexia nervosa (AN) in adults is difficult to treat, and no current treatment is supported by robust evidence. A few studies, most of which were performed by highly specialized research units, have indicated that enhanced cognitive behaviour
Stein Frostad, Yngvild S. Danielsen, Guro Å. Rekkedal, Charlotte Jevne, Riccardo Dalle Grave, Øyvind Rø, Ute Kessler   +6 more
doaj   +1 more source

Increased plasticity of the bodily self in eating disorders [PDF]

, 2011
Background: The rubber hand illusion (RHI) has been widely used to investigate the bodily self in healthy individuals. The aim of the present study was to extend the use of the RHI to examine the bodily self in eating disorders. Methods: The RHI and self-
Longo, Matthew R., J. Treasure, Treasure, J., Longo, M. R., Eshkevari, E., Rieger, E., M. R. Longo, E. Eshkevari, Haggard, P., E. Rieger, P. Haggard, Treasure, J.; id_orcid   +11 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

How a moderated online discussion forum facilitates support for young people with eating disorders [PDF]

, 2016
Introduction: Eating disorders in young people can be harmful to social, emotional and physical development and life chances. Young people with eating disorders encounter particular barriers to help-seeking.
Elvey, Rebecca, Pryjmachuk, Steven, Catchpole, R, Sue Kirk, Steven Pryjmachuk, Elvey, R, Sarah Kendal, Catchpole, Roger, Pryjmachuk, Steven; id_orcid, Rebecca Elvey, Kirk, Sue, Kendal, S, Pryjmachuk, S, Kendal, Sarah, Roger Catchpole, Kirk, Susan, Kirk, S   +16 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Case report: Anorexia nervosa and unspecified restricting-type eating disorder in Jewish ultra-orthodox religious males, leading to severe physical and psychological morbidity

Frontiers in Psychiatry, 2023
BackgroundYoung Jewish Ultra-Orthodox women usually show less disturbances in body image and eating in comparison to less religious communities. By contrast, problems with eating are highly unknown and unrecognized in Jewish Ultra-Orthodox males.AimTo ...
Sofia Laufer, Estee Herman, David Serfaty, Yael Latzer, Yael Latzer, Rachel Ashkenazi, Orna Attias, Sinai Oren, Meirav Shimomi, Moria Uziel, Adi Enoch-Levy, Eliezer Witztum, Daniel Stein, Daniel Stein, Daniel Stein   +14 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Extreme anorexia nervosa: medical findings, outcomes, and inferences from a retrospective cohort

Journal of Eating Disorders, 2020
Background Extreme anorexia nervosa (AN) is defined as a BMI
Dennis Gibson, Ashlie Watters, Jeana Cost, Margherita Mascolo, Philip S. Mehler   +4 more
doaj   +1 more source

Coping and Emotional Intelligence in Women with a History of Eating Disordered Behavior [PDF]

, 2006
Eating disorders pose a serious problem in our society. Studies have found that there is a negative correlation between eating disorders and emotional coping mechanisms, a factor of emotional intelligence (EI).
Boyd, Charlene
core