Results 41 to 50 of about 2,782 (162)

Improving Genotype Imputation in High‐Dimensional Pharmacogenomics Using Multiple Imputation: Evaluation with Machine Learning Approaches

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 964-978, April 2026.
Multiple imputation is well‐established for handling missing data, yet its use in high‐dimensional genetic datasets remains limited. Using pharmacokinetic tuberculosis simulations and SNP data (1000 Genomes Project), we compared machine learning (ML) and traditional approaches (e.g., mean imputation and complete‐case analysis) for imputation and ...
Innocent G. Asiimwe, Tao You, Daniel F. Carr, Munir Pirmohamed, Geraint Davies, Andrea L. Jorgensen, on behalf of the UNITE4TB Consortium   +6 more
wiley   +1 more source

Exploring the anticancer potential of Eleutherine bulbosa: A systematic network pharmacology study on lung cancer

Journal of Advanced Pharmaceutical Technology & Research
Chemotherapy application in lung cancer patients has several side effects and shows lower effectiveness due to chemoresistance. Although Eleutherine bulbosa (Mill.) Urb.
Roihatul Mutiah, Ermin Rachmawati
doaj   +1 more source

DELINEAMENTOS INTRASSUJEITOS NA AVALIAÇÃO DE PRÁTICAS PSICOEDUCACIONAIS BASEADAS EM EVIDÊNCIA

Psicologia em Estudo, 2019
Em diversos países, a educação baseada em evidências (EBE) ocupa um papel central na tomada de decisões acerca dos processos e procedimentos educacionais. No Brasil, a EBE ainda não é muito difundida na educação, mas dado o aumento gradual de publicações
Jackeline Joyce de Santana Santos, Ana Carolina Sella, Daniela Mendonça Ribeiro   +2 more
doaj   +1 more source

Towards a Novel Biocontrol Strategy: High Performance of Optimised Cell Wall‐Degrading Enzymes Secreted by Escovopsis primorosea LBM 277

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
Escovopsis primorosea LBM 277 efficiently produced proteases, β‐1,3‐glucanases and chitinases under submerged fermentation using Leucoagaricus gongylophorus cell walls and Mandels complex. RSM‐BBD optimization significantly increased enzyme activity. The enzymatic cocktail remained stable for 30 days at room temperature and pH 4–6, aligning with the ...
Marcela Paola Barengo, Natalia Soledad Amerio, Gustavo Ángel Bich, Pedro Darío Zapata, María Lorena Castrillo   +4 more
wiley   +1 more source

Integración de la enseñanza de la práctica de enfermería basada en la evidencia científica

Aquichan, 2015
En el 2002, la Facultad de Enfermería de la Pontificia Universidad Católica del Ecuador introdujo la enseñanza de la práctica basada en evidencia científica en el Proyecto de Reforma Curricular y Diversificación de Carreras y una década después se ...
Carmen Falconí Morales, Carmita Jannett Brito Santacruz, Irina Verkovitch   +2 more
doaj   +2 more sources

Gallium Nitride Semiconductor Resonant Tunneling Transistor

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Three‐terminal GaN semiconductor resonant tunneling transistors (RTTs), which comprise an double‐barrier AlN/GaN/AlN resonant tunneling diode integrated with a GaN high‐electron‐mobility transistor (HEMT) through epitaxial growth in series and parallel configuraions, respectively.
Fang Liu, JunShuai Xue, GuanLin Wu, JinYuan Yuan, JiaJia Yao, RenJie Liu, Zhuang Guo, ZeHui Li, HaoRan Hu, WenBo Sun, Cheng Zhao, ChenKai Zhang, XinYan Liu, Kai Zhang, JinCheng Zhang, Yue Hao   +15 more
wiley   +1 more source

Population pharmacokinetics and exposure–response analysis of durvalumab in patients with resectable stage II to IIIB (N2) NSCLC in the phase III AEGEAN study

British Journal of Clinical Pharmacology, Volume 92, Issue 3, Page 980-996, March 2026.
Aims In the AEGEAN study, perioperative durvalumab plus platinum‐based neoadjuvant chemotherapy for patients with resectable stage II to IIIB (N2) non‐small‐cell lung cancer (NSCLC) demonstrated a favourable benefit–risk profile. This study evaluated population pharmacokinetics (PopPK) and exposure–response (ER) relationships of durvalumab in patients ...
Xiaoying Zhao, Junjie Ding, Jiajia Zhao, Ling Zhang, Aburough Abegesah, Yu‐qian Zhang, Cathy O'Brien, Gary J. Doherty, Allen C. Chen, KyoungSoo Lim, Song Ren, Peiming Ma, Diansong Zhou   +12 more
wiley   +1 more source

Erzurum’daki kadınların gebelik sayısına ve aralığına etki eden faktörlerin incelenmesi

Ankara Sağlık Bilimleri Dergisi, 2015
Gebelikler arasındaki süre ve gebelik sayısı hem anne hem de fetal ve neonatal sağlık açısından önemlidir. Türkiye’de en yüksek gebelik oranı ve doğurganlık hızı Doğu Anadolu Bölgesinde görülmektedir.
Serap Ejder Apay, Funda Özdemir, Tuğçe Sakar, Yağmur Özorhan Elif   +3 more
doaj   +1 more source

Passive Gauze‐Based eDNA Sampler Proves Efficient and Cost‐Effective in the Marine Environment

Environmental DNA, Volume 8, Issue 2, March/April 2026.
Here, we present the first empirical comparison of the metaprobe 2.0, a low‐cost, passive eDNA sampler, against an industry standard Sterivex filtration method using dip‐collected 1‐L water samples (“water bottles”). Across 14 joint deployments, we assessed detection and quantification of eDNA of two elasmobranch and two teleost species. While Sterivex
Molly M. Kressler, Lucy Whitelegg, Benedict Tutt‐Leppard, Andrew Matthews, Dave Hudson, Richard B. Sherley   +5 more
wiley   +1 more source

Secrets within stems: The cryptic Apodanthes caseariae (Apodanthaceae), a rare neotropical holoendoparasite

PLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 385-400, March 2026.
Holoendoparasites are extremely rare plants that live entirely hidden inside their hosts, with only flowers and fruits visible. We studied Apodanthes caseariae, found in central and South America, parasitizing Casearia sylvestris. Little is known about its life cycle.
Jessica A. Ramírez‐Ramírez, Favio González, Estefanía Elejalde‐Baena, Juan F. Alzate, Natalia Pabón‐Mora   +4 more
wiley   +1 more source