Results 111 to 120 of about 67,833 (224)

Use of protective gear and the occurrence of occupational Marburg hemorrhagic fever in health workers from Watsa health zone, Democratic Republic of the Congo. [PDF]

, 2007
BACKGROUND: Occupational transmission to health workers (HWs) has been a typical feature of Marburg hemorrhagic fever (MHF) outbreaks. The goal of this study was to identify cases of occupational MHF in HWs from Durba and Watsa, Democratic Republic of ...
Libande, Modeste L, MULANGU, S, TSHOMBA, A, Pierre Lefèvre, Muyembe-Tamfum, J. J., Van der Stuyft, Patrick, LIBANDE, ML, Muyembe-Tamfum, Jean-Jacques, Kulidri, Amayo, Tshomba, Antoine, MUYEMBE-TAMFUM, JJ, BORCHERT, M, Antoine Tshomba, Borchert, M., Tshomba, A., Van der Stuyft, P., Libande, M. L., Jean‐Jacques Muyembe‐Tamfum, Modeste L. Libande, Kulidri, A., Amayo Kulidri, Matthias Borchert, Mulangu, Sabue, Mulangu, S., LEFEVRE, P, Sabue Mulangu, KULIDRI, A, Patrick Van der Stuyft, Borchert, Matthias, Lefevre, Pierre, Lefèvre, P.   +30 more
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Exosome‐Mediated Delivery of PROTACs for Targeted Protein Degradation in Cancer, Neurodegenerative, Infectious, and Inflammatory Diseases

Journal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are heterobifunctional molecules that hijack the ubiquitin‐proteasome system to drive catalytic, sub‐stoichiometric degradation of disease‐associated proteins, offering a mechanistic advantage over occupancy‐driven inhibitors and access to ‘undruggable’ targets.
Sruti Bagchi Ghosh, Rumpa Banerjee, Hailah M. Almohaimeed, Amany I. Almars, Tahani Ahmad ALMatrafi, Fayez M. Saleh, Zuhair M. Mohammedsaleh, Kranti Kiran Reddy Ealla, Ajoy Kumer, Bikram Dhara   +9 more
wiley   +1 more source

Ebola (Ebola virus disease) [French] [PDF]

Ebola (Ebola virus disease) [French]La maladie a\ucc\u20ac virus Ebola, connue auparavant sous le nom de fie\ucc\u20acvre he\ucc?morragique a\ucc\u20ac virus Ebola, est une maladie rare et mortelle, due a\ucc\u20ac l'infection par l'une des souches du ...

core  

Seroprevalence of Ebola virus infection in Bombali District, Sierra Leone

Journal of Public Health in Africa, 2017
A serosurvey of anti-Ebola Zaire virus nucleoprotein IgG prevalence was carried out among Ebola virus disease survivors and their Community Contacts in Bombali District, Sierra Leone. Our data suggest that the specie of Ebola virus (Zaire) responsible of
Nadege Goumkwa Mafopa, Gianluca Russo, Raoul Emeric Guetiya Wadoum, Emmanuel Iwerima, Vincent Batwala, Marta Giovanetti, Antonella Minutolo, Patrick Turay, Thomas B. Turay, Brima Kargbo, Massimo Amicosante, Mattei Maurizio, Carla Montesano, Ebola Study Group   +13 more
doaj   +1 more source

Comment on ‘Comparing specificity and seroconversion sensitivity among major blood screening assays for human immunodeficiency virus and viral hepatitis’

Vox Sanguinis, EarlyView.
Ramune Sepetiene, Mohamed Ali, Guillermo Orjuela, Ted Kieffer, Ellen Ollson, Axel Stover, Jason Kang   +6 more
wiley   +1 more source

Synthetic Ligands of Myeloid C‐Type Lectin Receptors

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Binding of ligands to C‐type lectin receptors (CLRs) on myeloid cells can lead to an array of cellular responses. Exploitation of these receptors for therapeutic purposes requires high‐affinity ligands. This review surveys the diversity of synthetic ligands of myeloid CLRs in the context of binding, signaling, and downstream effects, as well as ...
James Suri, Bernd Lepenies
wiley   +1 more source

Involvement of Surfactant Protein D in Ebola Virus Infection Enhancement via Glycoprotein Interaction

Viruses, 2018
Since the largest 2014–2016 Ebola virus disease outbreak in West Africa, understanding of Ebola virus infection has improved, notably the involvement of innate immune mediators.
Anne-Laure Favier, Olivier Reynard, Evelyne Gout, Martin van Eijk, Henk P. Haagsman, Erika Crouch, Viktor Volchkov, Christophe Peyrefitte, Nicole M. Thielens   +8 more
doaj   +1 more source

Identification and Optimization of a Truncated Hs‐1‐Derived Antimicrobial Peptide for Enhanced Broad‐Spectrum Antiviral Activity

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
Can a shorter peptide be a better antiviral? Structure‐guided optimization of the amphibian peptide Hs‐1 reveals a minimal α‐helical core that, after terminal modification, displays enhanced stability and submicromolar broad‐spectrum activity against enveloped viruses while maintaining a favorable safety profile. Antimicrobial peptides (AMPs) represent
Carla Zannella, Annalisa Chianese, Rosa Giugliano, Roberta Della Marca, Alessandra Monti, Martina Dragone, Gaetano Malgieri, Nunzianna Doti, Carla Isernia, Anna De Filippis, Massimiliano Galdiero   +10 more
wiley   +1 more source

Modeling Virus Dynamics by Colored Petri Nets: Ebola and COVID Case Study [PDF]

In this paper, we propose and explore Petri nets as a uniform formal language for modeling viruses that includes modeling behavior patterns, virus dynamics and immune response at cellular level and tempo-spatial modeling of infection spreading through ...
Formenti, R., Shmeleva, T.R., Zaitsev, D.   +2 more
core   +1 more source

Development of risk reduction behavioral counseling for Ebola virus disease survivors enrolled in the Sierra Leone Ebola Virus Persistence Study, 2015-2016. [PDF]

, 2017
BackgroundDuring the 2014-2016 West Africa Ebola Virus Disease (EVD) epidemic, the public health community had concerns that sexual transmission of the Ebola virus (EBOV) from EVD survivors was a risk, due to EBOV persistence in body fluids of EVD ...
Christine Ross, Tasneem Malik, Elizabeth Ervin, Kara N Durski, Thomas Massaquoi, Karen Kroeger, William J. Liu, William J Liu, Neetu Abad, Matthew Hogben, Suzanna L R McDonald, Anna Thorson, Patricia Ongpin, Kara N. Durski, Jaclyn Marrinan, Nathalie Broutet, Gibrilla F Deen, null null, Kyle Bernstein, Sierra Leone Ebola Virus Persistence Study Group, Barbara Knust, Archchun Ariyarajah, Suzanna L. R. McDonald, Gibrilla F. Deen   +23 more
core   +1 more source