Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer
Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley +1 more source
A Rare Case of Nodal T-follicular Helper Cell Lymphoma That Developed Cutaneous Lesions With Numerous Epstein-Barr Virus-Positive T Cells. [PDF]
Okamoto O +4 more
europepmc +1 more source
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng +20 more
wiley +1 more source
Epigenetic activation of EBV BGLF4 determines antiviral-based regimen response in EBV+CNS lymphoproliferative disease. [PDF]
Weigel C +20 more
europepmc +1 more source
AKTIV PULMONAR TUBERKULYOZDA CMV VA EBV KO‑INFEKSIYALARI
Muhammadjonova Dildora Baxromjon qizi +1 more
openalex +1 more source
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng +9 more
wiley +1 more source
Potential of non-specific blood biomarkers combined with EBV-specific antibodies for triaging in nasopharyngeal carcinoma screening. [PDF]
Zhuang C, Yi G, Lin H, Wang K.
europepmc +1 more source
CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang +17 more
wiley +1 more source
Interactions between hematological biomarkers of virus infection and immune cells in mediating distant metastasis in nasopharyngeal carcinoma: insights into prognosis and induction chemotherapy administration. [PDF]
Li S +12 more
europepmc +1 more source
Peritoneal Lymphomatosis as Posttransplant Lymphoproliferative Disorder
eJHaem, Volume 7, Issue 2, April 2026.
Shiori Nishitani +7 more
wiley +1 more source

