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Oral lichenoid lesions in CTLA‐4 haploinsufficiency: Targeting IFN‐γ‐driven mucosal immunopathology
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 10, Page e864-e867, October 2026.
Chen Wang +11 more
wiley +1 more source
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The roles of EBV-encoded microRNAs in EBV-associated tumors
Critical Reviews in Oncology/Hematology, 2019Epstein-Barr virus (EBV) is believed to be a pathogen causing a number of human cancers, but the pathogenic mechanisms remain unclear. An increasing number of studies have indicated that EBV-encoded microRNAs (EBV miRNAs) are expressed in a latency type- and tumor type-dependent manner, playing important roles in the development and progression of EBV ...
Jian-Ning Chen +2 more
exaly +3 more sources
2015
Although a role of EBV in autoimmunity is biologically plausible and evidence of altered immune responses to EBV is abundant in several autoimmune diseases, inference on causality requires the determination that disease risk is higher in individuals infected with EBV than in those uninfected and that in the latter it increases following EBV infection ...
Alberto, Ascherio, Kassandra L, Munger
openaire +2 more sources
Although a role of EBV in autoimmunity is biologically plausible and evidence of altered immune responses to EBV is abundant in several autoimmune diseases, inference on causality requires the determination that disease risk is higher in individuals infected with EBV than in those uninfected and that in the latter it increases following EBV infection ...
Alberto, Ascherio, Kassandra L, Munger
openaire +2 more sources
Immune defence against EBV and EBV-associated disease
Current Opinion in Immunology, 2011Epstein-Barr virus (EBV), a B-lymphotropic herpesvirus widespread in the human population and normally contained as an asymptomatic infection by T cell surveillance, nevertheless causes infectious mononucleosis and is strongly linked to several types of human cancer. Here we describe new findings on the range of cellular immune responses induced by EBV
Heather M, Long +2 more
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EBV+ lymphoproliferative diseases: opportunities for leveraging EBV as a therapeutic target
Blood, 2022Abstract Epstein-Barr virus (EBV) is a ubiquitous human tumor virus, which contributes to the development of lymphoproliferative disease, most notably in patients with impaired immunity. EBV-associated lymphoproliferation is characterized by expression of latent EBV proteins and ranges in severity from a relatively benign proliferative ...
Keri Toner, Catherine M. Bollard
openaire +2 more sources
Although the role of Epstein-Barr virus (EBV) in autoimmunity is biologically plausible and evidence of altered immune responses to EBV is abundant in several autoimmune diseases, inference on causality requires the determination that disease risk is higher in individuals infected with EBV than in those uninfected and that in the latter it increases ...
Marianna, Cortese +2 more
openaire +2 more sources
Marianna, Cortese +2 more
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Virus Research, 2002
EBV latent membrane protein 1 (LMP1) is essential for EBV-mediated transformation and has been associated with several cases of malignancies. EBV-like viruses in Cynomolgus monkeys (Macaca fascicularis) have been associated with high lymphoma rates in immunosuppressed monkeys. In the study, the entire coding region of the Cyno-EBV LMP1 gene was cloned,
Sylvie, Faucher +2 more
openaire +2 more sources
EBV latent membrane protein 1 (LMP1) is essential for EBV-mediated transformation and has been associated with several cases of malignancies. EBV-like viruses in Cynomolgus monkeys (Macaca fascicularis) have been associated with high lymphoma rates in immunosuppressed monkeys. In the study, the entire coding region of the Cyno-EBV LMP1 gene was cloned,
Sylvie, Faucher +2 more
openaire +2 more sources