Results 91 to 100 of about 1,782,169 (280)

Head and Neck Lymph Node Metastases From Cancer of Unknown Primary: Outcomes From p16‐Guided Mucosal Radiotherapy

Head &Neck, EarlyView.
ABSTRACT Background The AJCC 8th edition distinguishes p16‐positive oropharyngeal head and neck carcinoma of unknown primary (HNCUP) due to its superior prognosis. However, standardized radiation volume guidelines are lacking. This study evaluates the safety of p16‐guided mucosal volume reduction.
Philippe Harris, Dhiya‐Eddine Mabrouki, Felix‐Phuc Nguyen‐Tan, Edith Filion, Olivier Ballivy, Brian O'Sullivan, Apostolos Christopoulos, Tareck Ayad, Louis Guertin, Eric Bissada, Paul Tabet, Denis Soulières, Antoine Desilets, Alexandre Pellan Cheng, Robert Doucet, Laurent Létourneau‐Guillon, Houda Bahig   +16 more
wiley   +1 more source

Epstein-Barr Virus Infection Promotes Epithelial Cell Growth by Attenuating Differentiation-Dependent Exit from the Cell Cycle

mBio, 2019
Epstein-Barr virus (EBV) is a human herpesvirus that is associated with lymphomas as well as nasopharyngeal and gastric carcinomas. Although carcinomas account for almost 90% of EBV-associated cancers, progress in examining EBV’s role in their ...
Mark R. Eichelberg, Rene Welch, J. Tod Guidry, Ahmed Ali, Makoto Ohashi, Kathleen R. Makielski, Kyle McChesney, Nicholas Van Sciver, Paul F. Lambert, Sündüz Keleș, Shannon C. Kenney, Rona S. Scott, Eric Johannsen   +12 more
doaj   +1 more source

Pattern of Failure in Nasopharyngeal Carcinoma After Radiotherapy in a Low‐Incidence Population: A DAHANCA Study

Head &Neck, EarlyView.
ABSTRACT Background Nasopharyngeal carcinoma (NPC) is uncommon in many populations. Most existing clinical evidence comes from endemic areas, where Epstein–Barr virus (EBV)‐associated subtypes predominate. We analyzed patterns of failure in a population‐based cohort from Denmark, a low‐incidence setting.
Anne Marie Lindegaard, Katrin Haakansson, Maria Andersen, Mogens Bernsdorf, Jesper G. Eriksen, Mohammad Farhadi, Lisa L. Hjalgrim, Kenneth Jensen, Giedrius Lelkaitis, Christian Maare, Jens Overgaard, Christina Caroline Plaschke, Erik Schiess, Ruta Zukuskaite, Jeppe Friborg   +14 more
wiley   +1 more source

Epstein-Barr Virus Infection in Childhood May Precipitate Atopic Diseases

Allergology International, 2005
Background: Epstein Barr virus (EBV) has been suspected of being involved in the development of atopy. There are several studies suggesting a positive as well as negative association between EBV infection and atopic diseases. Here, we carried out a large-
Reiko Okudaira, Tokuko Mukoyama, Naohito Suzuki, Kohei Hashizume, Tsutomu Iwata, Fumiko Juji, Yoichi Kohno, Fujio Takeuchi, Hiroshi Shuto, Hirokazu Okudaira   +9 more
doaj   +1 more source

Association between composite dietary antioxidant index and Epstein–Barr virus infection in children aged 6–19 years in the United States: from the national health and nutrition examination survey 2007–2010

Frontiers in Nutrition
ObjectiveEpstein-Barr virus (EBV) is a globally prevalent herpes virus associated with multiple diseases. Oxidative stress is closely related to EBV infection, latency, reactivation, and transformation.
Wei Cheng, Yunfei Wang, Nan Ding, Rutao Xie   +3 more
doaj   +1 more source

Pretreatment EBV‐DNA/TLG‐Based Risk Stratification Is Associated With Survival Outcomes in Nonmetastatic Nasopharyngeal Carcinoma: An Exploratory Study

International Journal of Cancer, EarlyView.
ABSTRACT Whether combining pretreatment plasma Epstein–Barr virus DNA (EBV‐DNA) with 18F‐FDG PET/CT‐derived total lesion glycolysis (TLG) improves prognostic stratification in nonmetastatic nasopharyngeal carcinoma (NPC) is unclear, particularly in nonendemic populations.
Mehmet Çağrı Duymaz, Ece Özkaya Duymaz, Nazlı Ünsal, Recep Bekiş, Büşra Tozduman, Özgür Appak, Ayşe Demiral, Oğuz Çetinayak   +7 more
wiley   +1 more source

P1248: CTP SYNTHASE 1 IS A NOVEL TARGET IN T CELL CANCERS, WITH SMALL MOLECULE INHIBITION INDUCING DEATH OF NEOPLASTIC HUMAN T CELLS IN VITRO AND INHIBITION OF THEIR GROWTH IN AN IN VIVO XENOTRANSPLANT MODEL

HemaSphere, 2022
P. Beer, H. Asnagli, N. Minet, E. Hoeben, A. Parker, A. Fischer, S. Latour   +6 more
doaj   +1 more source

Epstein-Barr Virus Infection Alters Cellular Signal Cascades in Human Nasopharyngeal Epithelial Cells

Neoplasia: An International Journal for Oncology Research, 2006
Epstein-Barr virus (EBV) latent infection is a critical event in nasopharyngeal carcinoma (NPC) tumorigenesis. EBV-encoded genes have been shown to be involved in immune evasion and in the regulation of various cellular signaling cascades.
Angela Kwok Fung Lo, Kwok Wai Lo, Sai Wah Tsao, Hing Lok Wong, Jan Wai Ying Hui, Ka Fai To, S. Diane Hayward, Yiu Loon Chui, Yu Lung Lau, Kenzo Takada, Dolly P. Huang   +10 more
doaj   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Human Natural Killer Cells Prevent Infectious Mononucleosis Features by Targeting Lytic Epstein-Barr Virus Infection

Cell Reports, 2013
Primary infection with the human oncogenic Epstein-Barr virus (EBV) can result in infectious mononucleosis (IM), a self-limiting disease caused by massive lymphocyte expansion that predisposes for the development of distinct EBV-associated lymphomas. Why
Obinna Chijioke, Anne Müller, Regina Feederle, Mario Henrique M. Barros, Carsten Krieg, Vanessa Emmel, Emanuela Marcenaro, Carol S. Leung, Olga Antsiferova, Vanessa Landtwing, Walter Bossart, Alessandro Moretta, Rocio Hassan, Onur Boyman, Gerald Niedobitek, Henri-Jacques Delecluse, Riccarda Capaul, Christian Münz   +17 more
doaj   +1 more source