Results 181 to 190 of about 1,782,169 (280)

Identification of a Novel KRAS::ETNK1 Fusion Transcript in a Myelodysplastic/Myeloproliferative Overlap Syndrome With Eosinophilia: A Case Report

open access: yeseJHaem, Volume 7, Issue 6, December 2026.
ABSTRACT This work describes, to our knowledge, the first reported case of a patient with an MDS/MPN overlap syndrome harboring a novel KRAS::ETNK1 fusion transcript. The disease initially presented with eosinophilia, megakaryocyte expansion, mast cell infiltration, and a background of typical MDS/MPN‐associated mutations (ASXL1, TET2, EZH2, BCOR, and ...
Marianne Caledec   +17 more
wiley   +1 more source

Persistent Immune Thrombocytopenia as a Post‐Acute Sequelae of COVID‐19: A Case Report

open access: yesPublic Health Challenges, Volume 5, Issue 4, December 2026.
ABSTRACT Immune thrombocytopenia (ITP) is a recognized hematologic complication associated with coronavirus disease 2019 (COVID‐19), but its persistence years after acute infection remains uncommon. We present a case of a 52‐year‐old male who was diagnosed with COVID‐19 in June 2020. Following recovery from the acute illness, he had persistent fatigue,
Riazullah   +5 more
wiley   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, Volume 13, Issue 61, 3 November 2026.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li   +9 more
wiley   +1 more source

Reframing the Gut–Brain Axis: The Gut Wall as a Neural Immune Interface in Multiple Sclerosis and Autoimmune Neurological Diseases

open access: yesAnnals of Neurology, Volume 100, Issue 5, Page 915-930, November 2026.
Gut wall physiology in multiple sclerosis (MS) and autoimmune neurologic diseases remains underexplored but may span gut barrier dysfunction, enteric glial targeting, mucosal immune dysregulation, and autoimmune targets within the enteric nervous system (ENS).
Federico Montini   +4 more
wiley   +1 more source

Nasopharyngeal Carcinoma Mimicking Juvenile Nasopharyngeal Angiofibroma in an Adolescent Ghanaian Male: A Diagnostic Pitfall

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Nasopharyngeal carcinoma can mimic juvenile nasopharyngeal angiofibroma in adolescent males on both demographics and imaging; bilateral cavernous sinus involvement and sensorineural hearing loss are atypical for juvenile nasopharyngeal angiofibroma (JNA) and should prompt expedited tissue diagnosis even in settings where biopsy of a presumed ...
Dennis Brempong   +3 more
wiley   +1 more source

Hemophagocytic Lymphohistiocytosis in a Patient With Alcohol‐Associated Liver Disease: A Case Report Highlighting Diagnostic Challenges

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Hemophagocytic lymphohistiocytosis (HLH) is a life‐threatening hyperinflammatory syndrome with nonspecific clinical manifestations that can mimic common conditions in patients with alcohol dependence. Early clinical suspicion and rapid initiation of treatment are essential to prevent fatal outcomes.
Adalis Rivera   +4 more
wiley   +1 more source

SLE Complicated With AIHA and Parvovirus B19 Infection Secondary to PRCA: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
We report the diagnosis and treatment process of a female with SLE and AIHA infected with parvovirus B19 and secondary PRCA. Interestingly, there was no significant increase in hemoglobin after IVIG treatment for more than 50 days; however, the addition of foscarnet showed good efficacy.
Mingquan Xing   +4 more
wiley   +1 more source

Chronic Active Epstein–Barr Virus (EBV) Disease with Haemophagocytic Lymphohistiocytosis and Abnormal T/NK Cells

open access: yes
eJHaem, Volume 7, Issue 6, December 2026.
Buthaina Al Maashari   +4 more
wiley   +1 more source

Rapidly Progressing Interstitial Fibrosis and Glomerulonephritis due to Granulomatosis With Polyangiitis Presenting With Calf Pain

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT We describe a 51‐year‐old male presenting with bilateral calf pain and found to have rapidly progressing pulmonary‐renal syndrome due to GPA vasculitis, despite completing an empiric course of steroids for a gout flare. This case underscores the heterogeneous nature of GPA and the importance of early strong immunosuppressive therapy.
Lily Gupta (Allison)   +2 more
wiley   +1 more source

Randomized Phase II Trial of Consolidation Pembrolizumab After Definitive Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma: KCSG HN19‐09, CONPELAN Study

open access: yesHead &Neck, Volume 48, Issue 11, Page 3103-3112, November 2026.
ABSTRACT Background The benefit of consolidation programmed cell death protein 1 (PD‐1) blockade after chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma (NPC) remains unclear. Methods Patients with stages II–IVB NPC were randomized (2:1) to pembrolizumab 200 mg or placebo every 3 weeks for up to 17 cycles after chemoradiotherapy ...
Sang Hoon Chun   +11 more
wiley   +1 more source

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