Results 1 to 10 of about 125,177 (307)

Enhancement of specific T-lymphocyte responses by monocyte-derived dendritic cells pulsed with E2 protein of human papillomavirus 16 and human p16INK4A [PDF]

PeerJ, 2020
Introduction Prophylactic vaccines are already available for prevention of human papillomavirus (HPV) infection. However, we still await development of therapeutic vaccines with high efficiency for stimulating specific T lymphocytes to clear HPV ...
Nuchsupha Sunthamala, Neeranuch Sankla, Jureeporn Chuerduangphui, Piyawut Swangphon, Wanchareeporn Boontun, Supakpong Ngaochaiyaphum, Weerayut Wongjampa, Tipaya Ekalaksananan, Chamsai Pientong   +8 more
doaj   +2 more sources

Inherited immunodeficiencies associated with proximal and distal defects in T cell receptor signaling and co-signaling

Biomedical Journal, 2022
T lymphocytes are central cells of adaptive immunity. Activation of T lymphocytes by the antigen receptor of T cells (TCR) and co-stimulatory molecules involve specific signaling components and cascades.
Sylvain Latour
doaj   +1 more source

The interaction between Epstein–Barr virus and multiple sclerosis genetic risk loci: insights into disease pathogenesis and therapeutic opportunities

Clinical & Translational Immunology, 2023
Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune disease, characterised by the demyelination of neurons in the central nervous system. Whilst it is unclear what precisely leads to MS, it is believed that genetic predisposition combined ...
Ali Afrasiabi, Chantelle Ahlenstiel, Sanjay Swaminathan, Grant P Parnell   +3 more
doaj   +1 more source

Epstein Barr Virus related cancer in people living with HIV: a review of the literature [PDF]

World Cancer Research Journal, 2020
The introduction of Highly Active Antiretroviral Therapy (HAART) has modified the natural history of Human Immunodeficiency Virus (HIV) infection, leading to an increase in the life expectancy of the patients living with HIV (PLWH).
F. D’Andrea, E. Venanzi Rullo, A. Facciolà, M. Di Rosa, F. Condorelli, A. Marino, B. Cacopardo, G. Pellicanò, G. Nunnari, M. Ceccarelli   +9 more
doaj   +1 more source

Prevalence and association of Epstein-Barr virus infection with sinonasal inverted papilloma and sinonasal squamous cell carcinoma in the northeastern Thai population

Infectious Agents and Cancer, 2020
Aims Sinonasal inverted papillomas (SIP) and sinonasal squamous cell carcinomas (SNSCC) are sinonasal tumors with unclear etiology and pathogenesis. Epstein-Barr virus (EBV) has been detected in these tumors but information concerning their association ...
Thawaree Nukpook, Tipaya Ekalaksananan, Watchareporn Teeramatwanich, Natcha Patarapadungkit, Surachat Chaiwiriyakul, Patravoot Vatanasapt, Sirinart Aromseree, Chamsai Pientong   +7 more
doaj   +1 more source

Loss of RASGRP1 in humans impairs T‐cell expansion leading to Epstein‐Barr virus susceptibility

EMBO Molecular Medicine, 2018
Inherited CTPS1, CD27, and CD70 deficiencies in humans have revealed key factors of T‐lymphocyte expansion, a critical prerequisite for an efficient immunity to Epstein–Barr virus (EBV) infection.
Sarah Winter, Emmanuel Martin, David Boutboul, Christelle Lenoir, Sabah Boudjemaa, Arnaud Petit, Capucine Picard, Alain Fischer, Guy Leverger, Sylvain Latour   +9 more
doaj   +1 more source

Active Herpes Virus Infection in Young Children

Детские инфекции (Москва), 2018
Under observation were 122 young children (up to 3 years of age), who were identified markers of active forms of herpes virus infections. Markers were studied by PCR in blood, smear from tonsils, saliva, cerebrospinal fluid, urine with determination DNA ...
N. Yu. Egorova, O. V. Molochkova, L. N. Guseva, N. L. Waltz, K. P. Chusov   +4 more
doaj   +1 more source

The co-presence of high-risk human papillomaviruses and Epstein-Barr virus is linked with tumor grade and stage in Qatari women with breast cancer

Human Vaccines & Immunotherapeutics, 2021
High-risk human papillomaviruses (HPV) can be present and cooperate with Epstein–Barr virus (EBV) to promote the onset and/or progression of various cancers including cervical, breast, head and neck as well as colorectal.
Ishita Gupta, Ayesha Jabeen, Reem Al-Sarraf, Hanan Farghaly, Semir Vranic, Ali A. Sultan, Ala-Eddin Al Moustafa, Hamda Al-Thawadi   +7 more
doaj   +1 more source

THE RESULTS OF LONG-TERM STUDY OF HERPESVIRUS INFECTION AT THE DEPARTMENT OF INFECTIOUS DISEASES IN CHILDREN OF RUSSIAN NATIONAL RESEARCH MEDICAL UNIVERSITY

Детские инфекции (Москва), 2017
As a result of many years of research, the role of Herpesviridae IV, V and VI types in the structure of various pathologies in children (with infectious mononucleosis (MI), CNS damage, long-term subfebrile syndrome, vasculitis syndrome, hepatitis, etc ...
O. V. Shamsheva, F. S. Kharlamova, N. Yu. Egorova, O. V. Molochkova, E. V. Novosad, E. V. Simonova, T. M. Lebedeva, N. A. Guseva   +7 more
doaj   +1 more source

An impact of activated Epstein–Barr Virus and HHV-6 on the course and control of bronchial asthma in children of the Amur Region

Инфекция и иммунитет, 2022
The role of viral infection in bronchial asthma (BA) is well-known being reflected particularly in GINA. An effect of pneumotropic intracellular persistent herpesviruses on the course of BA is of particular interest. The most common viruses of this group
Evgeniy N. Suprun, Stefaniya V. Suprun, Marina A. Vlasova, Natalia I. Kuderova, Galina P. Evseeva, Olga A. Lebed'ko   +5 more
doaj   +1 more source