Results 1 to 10 of about 166,108 (310)

Enhancement of specific T-lymphocyte responses by monocyte-derived dendritic cells pulsed with E2 protein of human papillomavirus 16 and human p16INK4A [PDF]

open access: yesPeerJ, 2020
Introduction Prophylactic vaccines are already available for prevention of human papillomavirus (HPV) infection. However, we still await development of therapeutic vaccines with high efficiency for stimulating specific T lymphocytes to clear HPV ...
Nuchsupha Sunthamala   +8 more
doaj   +2 more sources

Inherited immunodeficiencies associated with proximal and distal defects in T cell receptor signaling and co-signaling

open access: yesBiomedical Journal, 2022
T lymphocytes are central cells of adaptive immunity. Activation of T lymphocytes by the antigen receptor of T cells (TCR) and co-stimulatory molecules involve specific signaling components and cascades.
Sylvain Latour
doaj   +1 more source

The interaction between Epstein–Barr virus and multiple sclerosis genetic risk loci: insights into disease pathogenesis and therapeutic opportunities

open access: yesClinical & Translational Immunology, 2023
Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune disease, characterised by the demyelination of neurons in the central nervous system. Whilst it is unclear what precisely leads to MS, it is believed that genetic predisposition combined ...
Ali Afrasiabi   +3 more
doaj   +1 more source

Epstein Barr Virus related cancer in people living with HIV: a review of the literature [PDF]

open access: yesWorld Cancer Research Journal, 2020
The introduction of Highly Active Antiretroviral Therapy (HAART) has modified the natural history of Human Immunodeficiency Virus (HIV) infection, leading to an increase in the life expectancy of the patients living with HIV (PLWH).
F. D’Andrea   +9 more
doaj   +1 more source

Prevalence and association of Epstein-Barr virus infection with sinonasal inverted papilloma and sinonasal squamous cell carcinoma in the northeastern Thai population

open access: yesInfectious Agents and Cancer, 2020
Aims Sinonasal inverted papillomas (SIP) and sinonasal squamous cell carcinomas (SNSCC) are sinonasal tumors with unclear etiology and pathogenesis. Epstein-Barr virus (EBV) has been detected in these tumors but information concerning their association ...
Thawaree Nukpook   +7 more
doaj   +1 more source

Impact of monotherapy on HIV-1 reservoir, immune activation, and co-infection with Epstein-Barr virus [PDF]

open access: yes, 2017
Objectives Although monotherapy (mART) effectiveness in maintaining viral suppression and CD4 cell count has been extensively examined in HIV-1-infected patients, its impact on HIV-1 reservoir, immune activation, microbial translocation and co-infection
Carmona, Francesco   +8 more
core   +11 more sources

Virological aspects of Epstein-Barr virus infections. [PDF]

open access: yes, 2005
Epstein-Barr virus (EBV) is usually maintained in an asymptomatic and latent form by the host immune system, and primarily by EBV-specific cytotoxic T cells (CTLs).
Kimura, Hiroshi   +2 more
core   +1 more source

Measurement of Epstein-Barr virus DNA load using a novel quantification standard containing two EBV DNA targets and SYBR Green I dye [PDF]

open access: yes, 2016
BACKGROUND Reactivation of Epstein-Barr virus (EBV) infection may cause serious, life-threatening complications in immunocompromised individuals. EBV DNA is often detected in EBV-associated disease states, with viral load believed to be a reflection of ...
Ausimmune Investigator Group (AIG)   +6 more
core   +1 more source

Epstein-Barr virus lytic infection promotes activation of Toll-like receptor 8 innate immune response in systemic sclerosis monocytes [PDF]

open access: yes, 2017
BACKGROUND: Monocytes/macrophages are activated in several autoimmune diseases, including systemic sclerosis (scleroderma; SSc), with increased expression of interferon (IFN)-regulatory genes and inflammatory cytokines, suggesting dysregulation of the ...
Dreyfus, David H.   +12 more
core   +1 more source

Identification of Epstein-Barr virus replication proteins in Burkitt’s lymphoma cells [PDF]

open access: yes, 2015
The working model to describe the mechanisms used to replicate the cancer-associated virus Epstein-Barr virus (EBV) is partly derived from comparisons with other members of the Herpes virus family.
Almohammad, Rajei   +8 more
core   +2 more sources

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