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EBV and Lymphomagenesis

open access: yesCancers, 2023
The clinical significance of Epstein–Barr virus (EBV) cannot be understated. Not only does it infect approximately 90% of the world’s population, but it is also associated with numerous pathologies. Diseases linked to this virus include hematologic malignancies such as diffuse large B-cell lymphoma, Hodgkin lymphoma, Burkitt lymphoma, primary CNS ...
Sausen, Daniel G.   +2 more
openaire   +2 more sources

Antiviral Drugs for EBV [PDF]

open access: yesCancers, 2018
Epstein–Barr virus (EBV) infects up to 95% of the adult human population, with primary infection typically occurring during childhood and usually asymptomatic. However, EBV can cause infectious mononucleosis in approximately 35–50% cases when infection occurs during adolescence and early adulthood.
Pagano, Joseph S.   +2 more
openaire   +3 more sources

Progress in EBV Vaccines [PDF]

open access: yesFrontiers in Oncology, 2019
The Epstein-Barr virus (EBV) is a ubiquitous pathogen that imparts a significant burden of disease on the human population. EBV is the primary cause of infectious mononucleosis and is etiologically linked to the development of numerous malignancies.
Dwain G. van Zyl   +7 more
openaire   +5 more sources

Extra-telomeric functions of telomerase in the pathogenesis of Epstein-Barr virus-driven B-cell malignancies and potential therapeutic implications [PDF]

open access: yes, 2018
The Epstein-Barr virus (EBV) is a ubiquitous human \u3b3-herpesvirus causally linked to a broad spectrum of both lymphoid and epithelial malignancies.
Celeghin, Andrea   +4 more
core   +1 more source

EBV and Lymphomagenesis

open access: yesUirusu, 2019
Epstein-Barr virus (EBV) is a double stranded DNA virus of the family Herpesviridae. EBV is associated with a variety of lymphomas, and the mechanisms by which it promotes lymphomagenesis have been elucidated; this includes, for example, by translocation/activation of Myc in Burkitt lymphoma.
Hiroshi, Kimura, Yusuke, Okuno
openaire   +3 more sources

Loss of RASGRP1 in humans impairs T‐cell expansion leading to Epstein‐Barr virus susceptibility

open access: yesEMBO Molecular Medicine, 2018
Inherited CTPS1, CD27, and CD70 deficiencies in humans have revealed key factors of T‐lymphocyte expansion, a critical prerequisite for an efficient immunity to Epstein–Barr virus (EBV) infection.
Sarah Winter   +9 more
doaj   +1 more source

EBV CHRONIC INFECTIONS

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2010
The infection from Epstein-Barr virus (EBV) or virus of infectious mononucleosis, together with other herpesviruses’ infections, represents a prototype of persistent viral infections characterized by the property of the latency. Although the reactivations of the latent infection are associated with the resumption of the viral replication and eventually
PIZZIGALLO, Eligio   +2 more
openaire   +6 more sources

The co-presence of high-risk human papillomaviruses and Epstein-Barr virus is linked with tumor grade and stage in Qatari women with breast cancer

open access: yesHuman Vaccines & Immunotherapeutics, 2021
High-risk human papillomaviruses (HPV) can be present and cooperate with Epstein–Barr virus (EBV) to promote the onset and/or progression of various cancers including cervical, breast, head and neck as well as colorectal.
Ishita Gupta   +7 more
doaj   +1 more source

Identification of type A and B isolates of Epstein-Barr virus by polymerase chain reaction [PDF]

open access: yes, 1990
A method is described for the identification of type A and type B isolates of Epstein-Barr virus (EBV) by means of the polymerase chain reaction. The use of three pairs of primers specific for genomic sequences coding for the two forms of EBV nuclear ...
Alliger, P.   +3 more
core   +1 more source

Active Herpes Virus Infection in Young Children

open access: yesДетские инфекции (Москва), 2018
Under observation were 122 young children (up to 3 years of age), who were identified markers of active forms of herpes virus infections. Markers were studied by PCR in blood, smear from tonsils, saliva, cerebrospinal fluid, urine with determination DNA ...
N. Yu. Egorova   +4 more
doaj   +1 more source

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