Results 1 to 10 of about 17,773 (204)

The Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) gH/gL Complex Is the Predominant Neutralizing Antigenic Determinant in KSHV-Infected Individuals [PDF]

open access: yesViruses, 2020
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the etiological agent of Kaposi’s sarcoma (KS), one of the most prevalent cancers of people living with HIV/AIDS in sub-Saharan Africa.
Tara Tran   +2 more
exaly   +4 more sources

Metabolic reprogramming and metabolic sensors in KSHV-induced cancers and KSHV infection [PDF]

open access: yesCell & Bioscience, 2021
Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic gammaherpesvirus associated with several human cancers. KSHV infection and KSHV-induced anabolic cell proliferation and cellular transformation depend on reprogramming of cellular metabolic ...
Tingting Li, Shou-Jiang Gao
doaj   +3 more sources

The Role of vIL-6 in KSHV-Mediated Immune Evasion and Tumorigenesis

open access: yesViruses
Kaposi’s sarcoma-associated herpesvirus (KSHV) is a double-stranded DNA gamma herpesvirus. Like other herpesviruses, KSHV establishes a latent infection with limited gene expression, while KSHV occasionally undergoes the lytic replication phase, which ...
Yoshihiro Izumiya, Tomoki Inagaki
exaly   +3 more sources

Suppression of DC-SIGN and gH Reveals Complex, Subset-Specific Mechanisms for KSHV Entry in Primary B Lymphocytes

open access: yesViruses, 2021
Kaposi sarcoma-associated herpesvirus (KSHV) is the causative agent of multiple cancers in immunocompromised patients including two lymphoproliferative disorders associated with KSHV infection of B lymphocytes.
Nancy Palmerin   +5 more
doaj   +1 more source

Investigation of CDH1 germline mutations in Turkish patients with Kaposi’s sarcoma

open access: yesTürk Biyokimya Dergisi, 2022
Kaposi’s sarcoma (KS) develops from the lining cells of blood or lymphatic vessels and may appear as red, purple, brown, or black lesions. E-cadherin, CDH1, is a cell adhesion molecule located on the surface of epithelial cells.
Celik Betul, Tuncer Seref Bugra
doaj   +1 more source

Non-human primate model of Kaposi's sarcoma-associated herpesvirus infection. [PDF]

open access: yesPLoS Pathogens, 2009
Since Kaposi's sarcoma-associated herpesvirus (KSHV or human herpesvirus 8) was first identified in Kaposi's sarcoma (KS) lesions of HIV-infected individuals with AIDS, the basic biological understanding of KSHV has progressed remarkably.
Heesoon Chang   +8 more
doaj   +1 more source

Update on Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) – review

open access: yesRomanian Journal of Internal Medicine, 2020
Human herpesvirus 8 (HHV8), also known as Kaposi sarcoma-associated herpesvirus (KSHV), is one of the few pathogens recognized as direct carcinogen, being involved in the pathogenesis of Kaposi sarcoma, primary effusion lymphoma and multicentric ...
Iftode Nicoleta   +3 more
doaj   +1 more source

The ubiquitin/proteasome system mediates entry and endosomal trafficking of Kaposi's sarcoma-associated herpesvirus in endothelial cells. [PDF]

open access: yesPLoS Pathogens, 2012
Ubiquitination, a post-translational modification, mediates diverse cellular functions including endocytic transport of molecules. Kaposi's sarcoma-associated herpesvirus (KSHV), an enveloped herpesvirus, enters endothelial cells primarily through ...
Whitney Greene   +5 more
doaj   +1 more source

Virally encoded interleukin-6 facilitates KSHV replication in monocytes and induction of dysfunctional macrophages.

open access: yesPLoS Pathogens, 2023
Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic double-stranded DNA virus and the etiologic agent of Kaposi's sarcoma and hyperinflammatory lymphoproliferative disorders.
Michiko Shimoda   +6 more
doaj   +1 more source

Establishment of Tree Shrew Animal Model for Kaposi’s Sarcoma-Associated Herpesvirus (HHV-8) Infection

open access: yesFrontiers in Microbiology, 2021
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the most common cause of Kaposi’s sarcoma (KS) and other malignant growths in humans. However, the lack of a KSHV-infected small animal model has hampered understanding of the mechanisms of KSHV infection,
Daoqun Li   +9 more
doaj   +1 more source

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