Results 21 to 30 of about 17,773 (204)
Viruses, 2014 Twenty years ago, Kaposi’s sarcoma (KS) was the oncologic counterpart to Winston Churchill’s Russia: a riddle, wrapped in a mystery, inside an enigma. First described by Moritz Kaposi in 1872, who reported it to be an aggressive skin tumor, KS became known over the next century as a slow-growing tumor of elderly men—in fact, most KS patients were ...
Chang, Y, Moore, P
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KSHV Genome Replication and Maintenance [PDF]
Frontiers in Microbiology, 2016 Kaposi's sarcoma associated herpesvirus (KSHV) or human herpesvirus 8 (HHV8) is a major etiological agent for multiple severe malignancies in immune-compromised patients. KSHV establishes lifetime persistence in the infected individuals and displays two distinct life cycles, generally a prolonged passive latent, and a short productive or lytic cycle ...
Purushothaman, Pravinkumar +4 more
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The relationship of adenoviruses to the DNA damage response protein BLM & Understanding the modulation of DNA repair pathways by the human oncogenic virus KSHV [PDF]
, 2011 Project 1: Adenoviruses (Ad) are able to interact with a number of proteins involved in the cellular response to DNA damage, in order to prevent concatamerisation of the viral genome and inhibition of viral replication.
Ryan, Ellis
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NEDDylation is essential for Kaposi's sarcoma-associated herpesvirus latency and lytic reactivation and represents a novel anti-KSHV target. [PDF]
, 2015 Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma (KS) and primary effusion lymphoma (PEL), which are aggressive malignancies associated with immunocompromised patients.
Wood, Jennifer J +19 more
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Towards Understanding KSHV Fusion and Entry
Viruses, 2019 How viruses enter cells is of critical importance to pathogenesis in the host and for treatment strategies. Over the last several years, the herpesvirus field has made numerous and thoroughly fascinating discoveries about the entry of alpha-, beta-, and ...
Stephen J. Dollery
doaj +1 more source
International Journal of Infectious Diseases, 2020 Objective: Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent for Kaposi's sarcoma (KS), one of the most common cancers in Tanzania. We have investigated KSHV prevalence and factors associated with KSHV infection in Tanzania.
Salum J. Lidenge +7 more
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Frontiers in Immunology, 2022 IntroductionFactors influencing Kaposi’s sarcoma-associated herpesvirus (KSHV) transmission and the early stages of KSHV infection in the human immune system remain poorly characterized.
Nedaa Alomari, Jennifer Totonchy
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Kaposi's sarcoma herpesvirus microRNAs target caspase 3 and regulate apoptosis [PDF]
, 2011 Kaposi's sarcoma herpesvirus (KSHV) encodes a cluster of twelve micro (mi)RNAs, which are abundantly expressed during both latent and lytic infection.
Contrant, M +60 more
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KSHV-mediated autophagy utilizes MK2.
, 2023 A: HUVECs were transduced with recombinant lentiviruses expressing shRNAs targeting MK2 or a non-targeting control (NS) and selected with puromycin (1 μg/mL). After selection, transduced cells were infected with wild-type (WT) or delete KapB (delB) BAC16
Jennifer A. Corcoran (13297021) +6 more
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Characteristics and outcomes of KSHV-associated multicentric Castleman disease with or without other KSHV diseases [PDF]
Blood Advances, 2021 Abstract Kaposi sarcoma (KS)-associated herpesvirus (KSHV)–associated multicentric Castleman disease (MCD) is a relapsing and remitting systemic lymphoproliferative disorder characterized by severe inflammatory symptoms most common among people living with HIV (PLWH).
Ramya Ramaswami +18 more
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