Results 21 to 30 of about 18,080 (165)

Towards Understanding KSHV Fusion and Entry

Viruses, 2019
How viruses enter cells is of critical importance to pathogenesis in the host and for treatment strategies. Over the last several years, the herpesvirus field has made numerous and thoroughly fascinating discoveries about the entry of alpha-, beta-, and ...
Stephen J. Dollery
doaj   +1 more source

Prevalence of Kaposi's sarcoma-associated herpesvirus and transfusion-transmissible infections in Tanzanian blood donors

International Journal of Infectious Diseases, 2020
Objective: Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent for Kaposi's sarcoma (KS), one of the most common cancers in Tanzania. We have investigated KSHV prevalence and factors associated with KSHV infection in Tanzania.
Salum J. Lidenge, Tara Tran, For Yue Tso, John R. Ngowi, Danielle M. Shea, Julius Mwaiselage, Charles Wood, John T. West   +7 more
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IL-21 signaling promotes the establishment of KSHV infection in human tonsil lymphocytes by increasing differentiation and targeting of plasma cells

Frontiers in Immunology, 2022
IntroductionFactors influencing Kaposi’s sarcoma-associated herpesvirus (KSHV) transmission and the early stages of KSHV infection in the human immune system remain poorly characterized.
Nedaa Alomari, Jennifer Totonchy
doaj   +1 more source

Kaposi's sarcoma herpesvirus microRNAs target caspase 3 and regulate apoptosis [PDF]

, 2011
Kaposi's sarcoma herpesvirus (KSHV) encodes a cluster of twelve micro (mi)RNAs, which are abundantly expressed during both latent and lytic infection.
Contrant, M, Johanna Viiliäinen, Vladimir Benes, Päivi M. Ojala, Voinnet Olivier, Gros, Frédéric, Voinnet, Olivier, Viiliainen, J, Mihaela Zavolan, Benes, Vladimir, Haas Juergen G., Suffert, G, Georg Malterer, Guillaume Suffert, Malterer, G, Frédéric Gros, Gros Frédéric, Ojala, Päivi M, Viiliäinen, Johanna, Suffert, Guillaume, Olivier Voinnet, Hausser Jean, Fender, A, Malterer Georg, Benes, V, Zavolan Mihaela, Ojala Päivi M., Haas, JG, Päivi M Ojala, Hausser, J, Viiliäinen Johanna, Zavolan, Mihaela, Hausser, Jean, Voinnet, O, Suffert Guillaume, Maud Contrant, Pfeffer Sébastien, Haas, Jürgen G., Zavolan, M, Jean Hausser, Tomi Ivacevic, Contrant Maud, Malterer, Georg, Benes Vladimir, Sébastien Pfeffer, Fender Aurélie, Haas, Juergen G, Ivacevic, T, Ojala, PM, Juergen G Haas, Ivacevic, Tomi, Aurélie Fender, Fender, Aurélie, Ojala, Päivi M., Pfeffer, Sébastien, Gros, F, Pfeffer, S, Contrant, Maud, Juergen G. Haas, Ivacevic Tomi, Haas, Juergen G.   +60 more
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Seroprevalence of Kaposi sarcoma-associated herpesvirus and other serologic markers in the Brazilian Amazon. [PDF]

, 2009
To determine the presence of Kaposi sarcoma-associated herpesvirus (KSHV) and other serologic markers, we tested serum specimens of 339 Amerindians, 181 rural non-Amerindians, and 1,133 urban blood donors (13 Amerindians) in the Brazilian Amazon.
Mascheretti, Melissa, Laura M. Sumita, Nascimento, Maria C, SUMITA, Laura M., Weiss, Helen A, NASCIMENTO, Maria C., Maria C. Nascimento, Sabino, Ester, Souza, Vanda U, VELA, Rodrigo A. R., Quiroga, Mariana, Melissa Mascheretti, SOUZA, Vanda U., PANNUTI, Claudio S., Mariana Quiroga, Vela, Rodrigo AR, Helen A. Weiss, Nuno R. Faria, Vanda U. Souza, Pannuti, Claudio S, Mayaud, Philippe, Rodrigo A.R. Vela, Sumita, Laura M, Oliveira, Juliane, Juliane Oliveira, Philippe Mayaud, Claudio S. Pannuti, WEISS, Helen A.   +27 more
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Dimethyl Sulfoxide Enhances Kaposi’s Sarcoma-Associated Herpesvirus Production During Lytic Replication

Frontiers in Microbiology, 2021
Kaposi’s sarcoma-associated herpesvirus (KSHV) is an etiologic agent of Kaposi’s sarcoma, primary effusion lymphoma, and multicentric Castleman disease. In studies of KSHV, efficient virus production and isolation are essential.
Su-Kyung Kang, Myung-Ju Lee, Ho-Hyun Ryu, Jisu Lee, Myung-Shin Lee, Myung-Shin Lee   +5 more
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The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin [PDF]

, 2010
Tetherin (CD317/BST2) is an interferon-induced membrane protein that inhibits the release of diverse enveloped viral particles. Several mammalian viruses have evolved countermeasures that inactivate tetherin, with the prototype being the HIV-1 Vpu ...
Wilson, Sam J., Calvi Alessandra, Towers, G.J., Trinity Zang, Stuart J D Neil, Claire Pardieu, Sam J Wilson, Wilson Sam J., Pardieu, C, Vigan, R., Zang, T, Towers, Greg J, Pardieu, Claire, Wilson, SJ, Neil Stuart J. D., Jung, J.U., Wilson, Sam J, Raphaël Vigan, Kellam, P, Pardieu, C., Towers, GJ, Neil, SJD, Bieniasz, P., Greg J Towers, Kellam, P., Neil, Stuart JD, Paul Kellam, Zang Trinity, Bieniasz Paul, Zang, T., Neil, S.J.D., Bieniasz, Paul, Alessandra Calvi, Towers Greg J., Vigan, Raphaël, Towers, Greg J., Wilson, S.J., Kellam Paul, Paul Bieniasz, Pardieu Claire, Calvi, A, Calvi, Alessandra, Neil, Stuart J. D., Kellam, Paul, Calvi, A., Bieniasz, P, Vigan Raphaël, Vigan, R, Zang, Trinity   +48 more
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Kaposi’s Sarcoma-Associated Herpesvirus and Host Interaction by the Complement System

Pathogens, 2020
Kaposi’s sarcoma-associated herpesvirus (KSHV) modulates the immune response to allow the virus to establish persistent infection in the host and facilitate the development of KSHV-associated cancer.
Seung-Min Yoo, Myung-Shin Lee
doaj   +1 more source

Metabolic reprogramming of Kaposi's sarcoma associated herpes virus infected B-cells in hypoxia. [PDF]

PLoS Pathogens, 2018
Kaposi's sarcoma associated herpesvirus (KSHV) infection stabilizes hypoxia inducible factors (HIFs). The interaction between KSHV encoded factors and HIFs plays a critical role in KSHV latency, reactivation and associated disease phenotypes.
Rajnish Kumar Singh, Fengchao Lang, Yonggang Pei, Hem Chandra Jha, Erle S Robertson   +4 more
doaj   +1 more source

The Significance of cGAS-STING Signaling in Response to Oncogenic Viruses. [PDF]

Cell Biochem Funct
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Guo L, Li L, Wang F, Liu W, Zhang Y.
europepmc   +2 more sources