Results 11 to 20 of about 17,773 (204)
Blood Advances, 2022 Kaposi sarcoma–associated herpesvirus (KSHV)/human herpesvirus 8–associated multicentric Castleman disease (MCD) is a polyclonal B-cell lymphoproliferative disorder that mainly occurs in immunocompromised hosts.
Chbihi, Marwa +47 more
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Frontiers in Microbiology, 2012 Soon after the discovery of Kaposi sarcoma (KS)-associated herpesvirus (KSHV), it was appreciated that this virus was associated with most cases of multicentric Castleman disease (MCD) arising in patients infected with human immunodeficiency virus.
Mark N. Polizzotto +3 more
doaj +2 more sources
Understanding KSHV vIRF-2-cell interactions [PDF]
, 2011 Kaposi’s sarcoma-associated herpes virus (KSHV) encodes genes with immunomodulatory potential, one of which is vIRF-2 that shares homology to cellular interferon regulatory factors.
Mutocheluh, Mohamed
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HIV Infection and Opioid Treatment Enable the Engraftment of Kaposi Sarcoma-Like Tumors Into Immunocompetent Mice. [PDF]
J Med VirolABSTRACT The Kaposi Sarcoma herpesvirus (KSHV) causes Kaposi sarcoma (KS), primary effusion lymphoma, a lymphoproliferative disease (KSHV‐multicentric Castleman's disease), and a cytokine inflammatory syndrome (KICS). These diseases occur more frequently, though not exclusively, among people living with HIV or other types of immune dysregulation. While
Naipauer J +10 more
europepmc +2 more sources
kshv-mir-k12-1-5p promotes cell growth and metastasis by targeting SOCS6 in Kaposi’s sarcoma cells
Cancer Management and Research, 2019 Jing Zhang,1,2 Xiong-Ming Pu,3 Yan Xiong41Postgraduate College of Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China; 2Department of Pathology, Affiliated Traditional Chinese Medicine Hospital, Xinjiang Medical University ...
Zhang J, Pu XM, Xiong Y
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The Significance of cGAS-STING Signaling in Response to Oncogenic Viruses. [PDF]
Cell Biochem FunctABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Guo L, Li L, Wang F, Liu W, Zhang Y.
europepmc +2 more sources
KSHV: forgotten but not gone [PDF]
Blood, 2011 Thirty years ago, Kaposi sarcoma (KS) arose as a prominent manifestation of the AIDS epidemic. Seventeen years ago we discovered the virus that causes KS,1 Kaposi sarcoma–associated herpesvirus (KSHV), and within a year KSHV had been also shown to be the likely cause of AIDS-associated primary effusion lymphoma (PEL)2 and most cases of multicentric ...
Moore, Patrick S., Chang, Yuan
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Cell Host & Microbe, 2013 In this issue of Cell Host & Microbe, Chang and Ganem (2013) report that Kaposi's sarcoma-associated herpesvirus infection of lymphatic endothelial cells (LECs), but not blood endothelial cells (BECs), activates mTORC1 signaling and sensitizes LECs to rapamycin-induced killing.
Yogev, Ohad, Boshoff, Chris
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KSHV: Immune Modulation and Immunotherapy [PDF]
Frontiers in Immunology, 2020 Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) is associated with KS, primary effusion lymphoma (PEL), and multicentric Castleman disease (MCD). To ensure its own survival and propagation, KSHV employs an extensive network of viral proteins to subvert the host immune system, resulting in lifelong latent infection.
Grant Broussard +4 more
openaire +3 more sources
Pan‐gammaherpesvirus control via a broadly neutralising gB antibody [PDF]
Clin Transl MedClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Jiang Z, Li P, Xie C, Sun C.
europepmc +2 more sources