Results 1 to 10 of about 8,714,646 (173)

Epigenetic Regulation of Kaposi’s Sarcoma-Associated Herpesvirus Latency

Frontiers in Microbiology, 2020
Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic γ-herpesvirus that infects humans and exhibits a biphasic life cycle consisting of latent and lytic phases.
Mel Campbell, Wan-Shan Yang, Wayne W. Yeh, Chen-Hsuan Kao, Pei-Ching Chang   +4 more
doaj   +1 more source

Immune reconstitution inflammatory syndrome, human herpesvirus 8 viremia, and HIV-associated multicentric Castleman disease

International Journal of Infectious Diseases, 2016
Kaposi's sarcoma and multicentric Castleman Disease are HIV-related disease processes that are associated with human herpesvirus 8 (HHV-8) infection.
Marc O. Siegel, Sanaz Ghafouri, Ravi Ajmera, Gary L. Simon   +3 more
doaj   +1 more source

Cells of the Innate and Adaptive Immune Systems in Kaposi’s Sarcoma

Journal of Immunology Research, 2020
Kaposi’s sarcoma (KS) is an angioproliferative malignancy whose associated etiologic agent is the Kaposi’s sarcoma-associated herpesvirus (KSHV). KS is the most prevalent malignancy among HIV-infected individuals globally and is considered an AIDS ...
Owen Ngalamika, Sody Munsaka
doaj   +1 more source

KSHV and Human Diseases: Beyond KS, PEL and MCD

Microorganisms
Kaposi’s Sarcoma-associated herpesvirus (KSHV) has been etiologically linked to several human cancers, including Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD). However, recent studies suggest that KSHV
Caroline Grace Firmin, Lu Dai, Zhiqiang Qin   +2 more
doaj   +1 more source

Novel Virus Related to Kaposi’s Sarcoma–Associated Herpesvirus from Colobus Monkey

Emerging Infectious Diseases, 2019
We determined the complete genome sequence of a virus isolated from a mantled guereza that died of primary effusion lymphoma. The virus is closely related to Kaposi’s sarcoma–associated herpesvirus (KSHV) but lacks some genes implicated in KSHV ...
Akshay Dhingra, Tina Ganzenmueller, Elias Hage, Nicolás M. Suárez, Kerstin Mätz-Rensing, Dimitri Widmer, Stefan Pöhlmann, Andrew J. Davison, Thomas F. Schulz, Artur Kaul   +9 more
doaj   +1 more source

Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6 promotes cell proliferation and migration by upregulating DNMT1 via STAT3 activation.

PLoS ONE, 2014
Kaposi's sarcoma-associated herpesvirus (KSHV) is etiologically associated with Kaposi's sarcoma (KS), the most common AIDS-related malignancy. KSHV vIL-6 promotes KS development, but the exact mechanisms remain unclear. Here, we reported that KSHV vIL-6
Jing Wu, Yuqiao Xu, Dongping Mo, Peijun Huang, Ruihong Sun, Lei Huang, Shiyang Pan, Jian Xu   +7 more
doaj   +1 more source

The Role of DNA Viruses in Human Cancer

Cancer Informatics, 2023
This review discusses the possible involvement of infections-associated cancers in humans, with virus infections contributing 15% to 20% of total cancer cases in humans.
Mehdi Fazlalipour, Zohreh-al-sadat Ghoreshi, Hamid Reza Molaei, Nasir Arefinia   +3 more
doaj   +1 more source

KSHV-Mediated Angiogenesis in Tumor Progression

Viruses, 2016
Human herpesvirus 8 (HHV-8), also known as Kaposi’s sarcoma-associated herpesvirus (KSHV), is a malignant human oncovirus belonging to the gamma herpesvirus family. HHV-8 is closely linked to the pathogenesis of Kaposi’s sarcoma (KS) and two other B-cell
Pravinkumar Purushothaman, Timsy Uppal, Roni Sarkar, Subhash C. Verma   +3 more
doaj   +1 more source

Celecoxib Inhibits the Lytic Activation of Kaposi’s Sarcoma-Associated Herpesvirus through Down-Regulation of RTA Expression by Inhibiting the Activation of p38 MAPK

Viruses, 2015
Kaposi’s sarcoma associated herpesvirus (KSHV) is the etiologic agent of Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD).
Jungang Chen, Liangyu Jiang, Ke Lan, Xulin Chen   +3 more
doaj   +1 more source

Hypoxic reactivation of Kaposi's sarcoma associated herpesvirus

Cell Insight
Hypoxic reactivation of Kaposi's sarcoma-associated herpesvirus (KSHV) refers to the phenomenon under low oxygen where the virus goes from latent to lytic replication.
Rajnish Kumar Singh, Atharva S. Torne, Erle S. Robertson   +2 more
doaj   +1 more source