Results 11 to 20 of about 13,850 (184)

Targeting of Prosurvival Pathways as Therapeutic Approaches against Primary Effusion Lymphomas: Past, Present, and Future [PDF]

, 2015
Constitutively activated prosurvival pathways render cancer cells addicted to their effects. Consequently they turn out to be the Achilles’ heels whose inhibition can be exploited in anticancer therapy.
CIRONE, Mara, FAGGIONI, Alberto, FARINA, Antonella, GONNELLA, ROBERTA, GRANATO, Marisa, SANTARELLI, Roberta, TRIVEDI, PANKAJ   +6 more
core   +4 more sources

Kaposi’s Sarcoma-associated herpesvirus microRNAs

Frontiers in Microbiology, 2012
Kaposi’s Sarcoma-associated herpesvirus (KSHV) is a human pathogenic -herpesvirus strongly associated with the development of Kaposi’s Sarcoma and B cell proliferative disorders, including primary effusion lymphoma (PEL).
Eva eGottwein
doaj   +1 more source

Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor induced growth arrest and apoptosis through NF-κB activation [PDF]

, 2013
Kaposi's sarcoma-associated herpesvirus (KSHV) has been linked to the development of Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease (MCD). We have characterized the role of KSHV-encoded viral FLICE inhibitory protein K13
Ahmad, B. Tolani, Ballon, Benhamou, Bower, Bren, C. Graham, Chang, Chaudhary, Chugh, Delmore, Dong, Du, Dupin, Dupin, Eeva, Eeva, Field, Gerondakis, Guasparri, H. Matta, H. Yi, Hassman, Herzog, Lee, Liu, Madureira, Matta, Matta, Matta, Matta, Mineva, Nador, Niiro, P. M. Chaudhary, Parravicini, Punj, Schauer, Soulier, Sun, Sun, Sun, Thome, Vrzalikova, Waterston, Wu, Wu, Wu, Y. Suo, Y. Yang, Yang, Yang, Young, Zhao   +53 more
core   +1 more source

Disseminated HIV-Associated Kaposi’s Sarcoma With High CD4 Cell Count And Low Viral Load

Galicia Clínica, 2017
Kaposi’s sarcoma is considered an acquired immunodeficiency syndrome-defining illness and is caused by human herpesvirus 8. It has been associated with patients infected with human immunodeficiency virus (HIV) who have CD4 T lymphocytes
Diana Pereira Anjos, Ana João Sá, André Paupério, Mari Mesquita   +3 more
doaj   +1 more source

KSHV Genome Replication and Maintenance [PDF]

, 2016
Kaposi’s sarcoma associated herpesvirus (KSHV) or human herpesvirus 8 (HHV8) is a major etiological agent for multiple severe malignancies in immunocompromised patients.
Namrata Gupta, Pravinkumar Purushothaman, Prerna Dabral, Roni Sarkar, Subhash C. Verma   +4 more
core   +6 more sources

Non-detection of human herpesvirus 8 (HHV-8) DNA in HHV-8-seropositive blood donors from three Brazilian regions. [PDF]

PLoS ONE, 2011
Human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV), is the etiologic agent of all forms of Kaposi's sarcoma, primary effusion lymphoma and the plasmablastic cell variant of multicentric Castleman disease. In endemic
José Eduardo Levi, Maria Claudia Nascimento, Laura Masami Sumita, Vanda Akico Ueda Fick de Souza, Wilton S Freire, Philippe Mayaud, Claudio S Pannuti   +6 more
doaj   +1 more source

Short communication: NKG2C+ NK cells contribute to increases in CD16+CD56- cells in HIV type 1+ individuals with high plasma viral load. [PDF]

, 2012
Chronic HIV-1 infection results in the expansion of both NKG2C+ and CD16+CD56- human natural killer cells. NKG2C+ cells proliferate in response to human cytomegalovirus (HCMV) and expansion of the dysfunctional CD56-CD16+ natural killer (NK) cells is ...
Bower, Mark, Gazzard, Brian G, Goodier, Martin R, Gregson, John NS, Kuri-Cervantes, Leticia, Mela, Christopher M   +5 more
core   +1 more source

Unusual immunophenotypic variant of large B-cell lymphoma associated with HHV-8 and EBV in an HIV positive patient

Human Pathology: Case Reports, 2015
Human herpesvirus type 8, also known as Kaposi's sarcoma-associated herpesvirus (HHV-8/KSHV) has been associated with several lymphoproliferative disorders including Kaposi's sarcoma, primary effusion lymphoma (PEL), cases of multicentric Castleman's ...
Roberto Ruiz-Cordero, MD, Jenna Lewis, MD, Clifford Blieden, MD, German Campuzano-Zuluaga, MD, Jose Hernandez, MD, Izidore S. Lossos, MD, Francis Ikpatt, MD, Jennifer R. Chapman, MD, Francisco Vega, MD, PhD   +8 more
doaj   +1 more source

Potential Application of the CRISPR/Cas9 System against Herpesvirus Infections. [PDF]

, 2018
The CRISPR/Cas9 system has been applied in the genome editing and disruption of latent infections for herpesviruses such as the herpes simplex virus, Epstein⁻Barr virus, cytomegalovirus, and Kaposi's sarcoma-associated herpesvirus.
Chen, Yuan-Chuan, Liu, Fenyong, Sheng, Jingxue, Trang, Phong   +3 more
core   +2 more sources

Kaposi's sarcoma-associated herpesvirus infection and Kaposi's sarcoma in Brazil

Brazilian Journal of Medical and Biological Research, 2006
Kaposi's sarcoma (KS) became a critical health issue with the emergence of acquired immunodeficiency syndrome (AIDS) in the 1980s. Four clinical-epidemiological forms of KS have been described: classical KS, endemic KS, iatrogenic KS, and AIDS-associated
S. Ramos-da-Silva, D. Elgui-de-Oliveira, L. Borges, C.E. Bacchi   +3 more
doaj   +1 more source